ONG-TERM 24-HOUR INTRAOCULAR PRESSURE CONTROL AND PROGRESSION RATE OBTAINED WITH THE ASSOCIATION OF COMBIGAN IN THE MORNING AND GANFORT IN THE EVENING COMPARED WITH LATANOPROST IN HIGH RISK OPEN-ANGLE GLAUCOMA.
- Conditions
- Patients with glaucoma open angle or glaucoma exfoliative with high risknewly diagnosed and untreated.Therapeutic area: Diseases [C] - Eye Diseases [C11]
- Registration Number
- EUCTR2013-001634-17-IT
- Lead Sponsor
- AZIENDA OSPEDALIERA S. PAOLO
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- 60
-Newly diagnosed untreated patients;
-Willingness to comply with the investigator’s and protocol’s instructions;
->21 years of age;
-IOP equal to 27 mm Hg or more, at 10:00 am;
-Early to moderate POAG or XFG, exhibiting a visual field damage between –5 dB and -12 dB;
-High risk profile for progression.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 30
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 30
- < 21 years of age;
- On any medication that can interfere with study drugs;
- Any comorbidity that could interfere with disease progress or VF reading;
- Ocular surgery within last 6 months;
- Pregnancy;
- Allergic or intolerable to any components in study drugs;
- Participating in any other study;
- Inability to give informed consent;
-Reactive airway disease, second or third degree heart block, poorly compensated congestive heart failure or concomitant use of systemic beta-blockers.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method