Efficacy of Vamana Karma or Virechana Karma followed by Patoladi Kwatha and Patoladi Kwatha alone in the management of Amlapitta w.s.r. to Hyperacidity:An Open Labelled Randomized Comparative Clinical Trial

Introduction:

Poor and inadequate dietary habits result in the imbalance and dysfunction of Annavaha strotas, leading to various disorders, one of which is Amlapitta. Acharya Vagbhata has stated that all diseases are caused by Mandagni. Which negatively affects the Samana and Udana Vayu as both Vayu are responsible for proper digestion. In the present modern era, fast hectic lifestyle, mental stress, incompatible food habits, unhealthy regimens habits like smoking, alcohols etc. Which are not suitable for the physiology of digestion and Willful medications like NSAIDS, steroids, some vitamin supplements, insufficient sleep at night, irregular meal pattern, eating to late at night, spicy, salty and sour foods, suppression of urges are causing gastric irritation and hyper gastric secretions leading to the onset of Amlapitta.

Significance:

In Western countries, hyperacidity is a common complaint. Studies indicate that up to 20-30% of adults experience symptoms of gastroesophageal reflux disease (GERD), which is closely related to hyperacidity. In developing countries, the prevalence of hyperacidity may be lower but is rising due to changes in diet and lifestyle. Urbanization and increased consumption of processed food are contributing factors. Amlapitta involve three important factor i.e. Agnimandya, Ama and Annavaha Srotodusti, Vamana is best treatment modality in Kapha vridhhi hence Vamana has been planned. As Amlapitta causes vitiation of Pitta leading to qualitative and quantitative increase of Pachaka Pitta especially in its Amla and Drava guna so Virechana has been planned to pacify the Pitta dosha in another group as comparator to treat the patients of Amlapitta. In Shamana Chikitsa, Ayurveda have mentioned the drug, which are having Tikta and Madhura-Rasa, Sheeta-Virya and Katu-Vipaka, Laghu and Ruksha guna. Hence Patoladi Kwatha will be used for pana.

Aim & Objectives:

Aims:

To compare the efficacy of Vamana Karma or Virechana Karma followed by Patoladi Kwatha and Patoladi Kwatha alone in the management of Amlapitta.

Objectives:

1. To assess the efficacy of Vamana Karma followed by Patoladi Kwatha in the management of Amlapitta.

2. To assess the efficacy of Virechana Karma followed by Patoladi Kwatha in the management of Amlapitta.

3. To assess the efficacy of Patoladi Kwatha alone in the management of Amlapitta.

Materials and methods:

30 Diagnosed and newly diagnosed patients of Amlapitta will be enrolled in three groups. Group A patients will receive intervention with Vamana Karma followed by Patoladi Kwatha. Group B Patients will receive Virechana Karma followed by Patoladi Kwatha. Group C Patients will receive Patoladi Kwatha.

Results and Discussion:

Data generated during the above study will be present in a systemic manner as shall be analyzed statically. Where the important points of the Conceptual study, Analytical study, Pharmacological study will be discussed.

Follow up:

After completion of therapy, follow up will be done after 15 days to assess the status of patient, where patient will be asked to report.

Adverse effects:

This drug have no known unwanted effects.Adverse Drug Reaction if any observed will  be reported to the Pharmacovigilance cell of I.R.A Jamnagar .