Blood Pressure Control in ESH Excellence Centres

• Conditions: Blood Pressure; White Coat Hypertension; Lifestyle Risk Reduction

• Registration Number: NCT04295434
• Lead Sponsor: Clinical Hospital Centre Zagreb

Brief Summary

In the BP-CON-ESH study we are going to include and analyze treated hypertensive patients seen consecutively by the ESH Excellence Centres. Blood pressure will be measured as usually done in the office, but care will be adopted to make measurements highly standardized in all Centres. The primary goals will be to determine the global, regional and country rates of hypertension control in Europe. Other goals will be to identify global and regional factors associated with blood pressure control in different European regions. The results obtained in the BP-CON-ESH project will be used to refine treatment strategies for improvement of blood pressure control and will serve as a basis for assessing future changes and trends in Europe.

Detailed Description

The most important task of the European Society of Hypertension is to improve blood pressure treatment and increase blood pressure control, thus decreasing cardiovascular risk, premature cardiovascular and renal morbidity and mortality, with in addition a reduction of health-care costs. More than a decade ago, the European Society of Hypertension established a network of Excellence Centres. Those centres are leading institutions for the diagnosis and treatment of hypertension and thus are front runners of good clinical practice in hypertension management in their countries. An important task of the Excellence Centres is also to be active in research, particularly in projects conducted by the European Society of Hypertension. The ongoing BP-CON-ESH project on the rate of blood pressure control in hypertensive patients addresses the most elementary,but at the same timethe most important aspect in hypertension management, because the observed low rates of blood pressure control is the reason why hypertension is still today the leading cause of death worldwide.

In the BP-CON-ESH study we are going to include and analyze treated hypertensive patients seen consecutively by the ESH Excellence Centres. Blood pressure will be measured as usually done in the office, but care will be adopted to make measurements highly standardized in all Centres.

The primary goals will be to determine the global, regional and country rates of hypertension control in Europe. Other goals will be to identify global and regional factors associated with blood pressure control in different European regions. It is well known that the overall control of hypertension in Europe is still insufficient. However, the problem is not the same across Europe. Differences in healthcare systems exist among European countries, and in some countries government healthcare system only partially reimburse costs of antihypertensive therapy. There are also differences in gross national product, educational levels, salt consumption, prevalence of obesity and other aspects. These could cause dissimilarities in hypertension prevalence, achieved blood pressure control and cardiovascular mortality among European regions.

The results obtained in the BP-CON-ESH project will be used to refine treatment strategies for improvement of blood pressure control and will serve as a basis for assessing future changes and trends in Europe.

Study Timeline

• Study Start: 2018-10-01
• Study First Submitted: 2020-02-26
• Status Verified: 2020-03
• Study First Submitted QC: 2020-03-03
• Last Update Submitted: 2020-03-03
• Study First Posted: 2020-03-04
• Last Update Posted: 2020-03-04
• Primary Completion: 2020-10-01
• Study Completion: 2021-03-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 3000

Inclusion Criteria

• Signed informed consent

Exclusion Criteria

• Pregnancy and breastfeeding
• Terminal malignancy, reduced life expectancy (<6 months)
• Amputated limb
• Dementia
• Patients living in a nursing home
• Unsigned informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Blood pressure control	Through study completion, an average of 1 year	Difference in blood pressure values between ESH Excellence Centres

Trial Locations

Locations (46)

Center of Preventive Cardiology, Yerevan; 🇦🇲 Yerevan, Armenia

University of Athens, Hippokration Hospital; 🇬🇷 Athens, Greece

Hypertension Center, Department of Nephrology, University Hospital of Ioannina; 🇬🇷 Ioánnina, Greece

Klinikum Wels-Grieskirchen; 🇦🇹 Wels, Austria

Ambroise Paré University Hospital; 🇧🇪 Mons, Belgium

Hypertension Center Munich; 🇩🇪 Munich, Germany

Hypertension Clinic, Department of Cardiology, KAT General Hospital; 🇬🇷 Athens, Greece

University Hospital of Heraklion; 🇬🇷 Heraklion, Greece

Hypertension Clinic, Cardiology Department, Asklepeion Hospital; 🇬🇷 Athens, Greece

Hypertension Center, Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki; 🇬🇷 Thessaloníki, Greece

Aristotle University of Thessaloniki, Papageorgiou General Hospital; 🇬🇷 Thessaloníki, Greece

American University Center, Hypertension/Vascular Medicine Division (Associated Centre); 🇱🇧 Beirut, Lebanon

University Hospital Maastricht; 🇳🇱 Maastricht, Netherlands

National Scientific Center "The M.D. Strazhesko Institute of Cardiology"; 🇺🇦 Kyiv, Ukraine

University Hospital "St. Anna"; 🇧🇬 Sofia, Bulgaria

Hypertension Center Berlin Charité; 🇩🇪 Berlin, Germany

University hospital centre Zagreb; 🇭🇷 Zagreb, Grad Zagreb, Croatia

Tallinn Hypertension Excellence Centre; 🇪🇪 Tallinn, Estonia

Hypertoniezentrum Bonn; 🇩🇪 Bonn, Germany

Institute for Clinical and Experimental Medicine (IKEM) and Thomayer Hospital, Prague; 🇨🇿 Praha, Czechia

Erasmus Hospital; 🇧🇪 Brussels, Belgium

CHU de Liège; 🇧🇪 Liège, Belgium

Charles University Medical School and University Hospital; 🇨🇿 Plzen, Czechia

Medizinische Hochschule Hannover; 🇩🇪 Hanover, Germany

Universitätskliniken des Saarlandes; 🇩🇪 Homburg, Germany

Hypertension Clinic, University Hospital Laiko; 🇬🇷 Athens, Greece

Hypertension and Cardiovascular Prevention Clinic, 3rd Department of Medicine, Evangelismos Hospital; 🇬🇷 Athens, Greece

Hypertension Outpatient Clinic, 1st Propedeutic Dept. of Internal Medicine, AHEPA Hospital; 🇬🇷 Thessaloníki, Greece

Assuta Ashdod University Hospital; 🇮🇱 Ashdod, Israel

Centre of Prevention and Treatment of Arterial Hypertension and Cardiovascular Risk Factors; 🇮🇹 Brescia, Italy

S. Luca Hospital, Istituto Auxologico Italiano; 🇮🇹 Milan, Italy

Ospedale Niguarda, Dip. De Gasperis e Università di Milano Bicocca; 🇮🇹 Milan, Italy

Napoli Hypertension Excellence Centre, Federico II Clinic Research Center for Hypertension and Related Conditions; 🇮🇹 Napoli, Italy

Excellence Centre of Hypertension, Department of Medical Sciences, University of Torino; 🇮🇹 Torino, Italy

Kaunas Hypertension Excellence Centre; 🇱🇹 Kaunas, Lithuania

Radboud University of Nijmegen Medical Center; 🇳🇱 Nijmegen, Netherlands

Department of Internal Medicine, Hypertension and Vascular Diseases, Warsaw Medical University; 🇵🇱 Warsaw, Poland

Centro Hospitalar do Alto Ave, Minho University; 🇵🇹 Guimarães, Portugal

Department of Cardiology and Internal Medicine, Emergency Clinical Hospital of Bucharest; 🇷🇴 Bucharest, Romania

Centre for Hypertension of the Clinical Centre of Serbia; 🇷🇸 Belgrad, Serbia

Hipertensión Clinic, Internal Medicine, Hospital Clinico, University of Barcelona; 🇪🇸 Barcelona, Spain

Danderyd University Hospital; 🇸🇪 Stockholm, Sweden

Hypertension Clinic, Nephrology Department, Reina Sofia University Hospital; 🇪🇸 Córdoba, Spain

St. Bartholomew's Royal London School of Medicine & Dentistry; 🇬🇧 London, United Kingdom

The Pearl-Rose Clinic (Hypertension & Cardiovascular Risk), Hammersmith Hospital,; 🇬🇧 London, United Kingdom

Center for Hypertension, Charles University, Prague; 🇨🇿 Praha, Czechia