The Effect of Dental Laser Therapy for Patients With Systemic Lupus Erythematosus
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 91
- 试验地点
- 1
- 主要终点
- pain value
研究概览
简要总结
Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease that has detrimental effects on connective tissue and other organs. The musculoskeletal system is one of the most affected systems in this group of patients including the temporomandibular joint. The most common symptoms when muscle involvement in SLE are muscle atrophy decreased muscle strength and myopathy. SLE activity and long-term corticosteroid use are thought to be responsible for these symptoms, thus, SLE patients are accepted to be at higher risk for temporomandibular joint disorders (TMD). Low-level laser therapy(LLLT) is frequently used in the treatment of TMD due to its pain relief and anti-inflammatory effect. Thus, in this study, LLLT has been used to evaluate this treatment modality on the chewing function and pain values of SLE patients with myogenic TMD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Having myogenic temporomandibular joint disorder,
- •Following a stable medical regime,
- •Showing minimum pain intensity of 50 mm on the visual analog scale.
排除标准
- •Having concurrent systemic diseases,
- •Using antimalarial drugs,
- •Wearing removable prosthesis,
- •History of facial trauma.
研究组 & 干预措施
test group
SLE patients treated with infrared laser irradiation
干预措施: GaAlAs semiconductor diode laser device (Device)
placebo group
SLE patients treated with red laser irradiation
干预措施: GaAlAs semiconductor diode laser device (Device)
control group
no therapy group
结局指标
主要结局
pain value
时间窗: 2 months
Pain intensity was evaluated by using Visual Analog Scale(VAS).
chewing function
时间窗: 2 months
The chewing function was evaluated by measuring the geometric mean diameter of crushed test food.
次要结局
未报告次要终点
研究者
Dr. Merve Benli
Assistant Professor
Istanbul University
