Observational study of in vivo forces and musculoskeletal loading conditions in fracture healing

Recruiting

• Conditions: S82.1; S82.2; S82.3; S82.7; S72; Fracture of upper end of tibia; Fracture of shaft of tibia; Fracture of lower end of tibia; Multiple fractures of lower leg; Fracture of femur

• Registration Number: DRKS00034409
• Lead Sponsor: Charité - Universitätsmedizin Berlin, Julius Wolff Institut

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-06-05
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Adult, legally competent, all patients who understand and sign the consent form to participate in the study, fracture of the long bones (femur or tibia), osteosynthetic treatment, were mobile preoperatively.

Exclusion Criteria

Motor or other medical limitations that do not allow movement analysis, osteoporosis or cancer, non-attendance at examination appointments.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of healing quality using the radiographic score [modified Radiographic Union Score for Tibial Fractures (mRUST)] and measurement of interfragmentary motion in patients by fluoroscopy.

Secondary Outcome Measures

Name	Time	Method
Clinical scores: PROMs [Visual analog scale (VAS), pressure pain, SF-36 / Knee Society Score (KSS)]; biomechanical function improvement: ground reaction forces [symmetry to contralateral], Short Physical Performance Battery [SPPB]).