:Effects of Pharmaceutical Care in Stroke Patients
- Conditions
- Stroke
- Interventions
- Behavioral: Clinical Pharmacist Led Pharmaceutical Care
- Registration Number
- NCT06129318
- Lead Sponsor
- Marmara University
- Brief Summary
To evaluate the effects of the 1-year pharmaceutical care program offered by the clinical pharmacist to the patients admitted to the neurology service with the diagnosis of stroke, on medication adherence, quality of life, and clinical outcomes of the patients.
- Detailed Description
The study was conducted as a parallel randomized controlled study in the Neurology Clinic of a University Hospital in Turkey. Patients were randomly assigned to intervention and usual care groups. While the patients in the usual care group are given routine health services by the neurologist during their hospitalization and for 1 year after discharge; In addition to these routine services, the intervention group was provided with pharmaceutical care by a clinical pharmacist during the same period. The study was always conducted by the same neurologist and clinical pharmacist. Patient medication adherence, quality of life, and clinical parameters were evaluated at the beginning of the study and at the 12th month.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 260
- being diagnosed with stroke,
- being 18 years old or older,
- being in the cognition to receive the training to be given
- Not having adequate cognitive function such as dementia,
- being pregnant, lactating,
- having cancer.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Clinical Pharmacist Led Pharmaceutical Care Clinical Pharmacist Led Pharmaceutical Care In addition to usual care services, the intervention group was provided with pharmaceutical care by a clinical pharmacist.
- Primary Outcome Measures
Name Time Method Blood pressure 1, 3, 6, 9 and 12 months Blood pressure was checked and recorded by a qualified nurse during the hospital stay and at control visits. Measurements were recorded as mmHg.
Medication Adherence 3, 6, 9 and 12 months Adherence to Stroke Prevention Medications (Anti platelets, Anticoagulants, Statins, antihypertensives, antidiabetics) measured by Morisky-Green-Levine Adherence Scale (1-4) where higher scores indicate higher levels of reported adherence.
HbA1c 1, 3, 6, 9 and 12 months HbA1c (glycated hemoglobin) value was collected from medical records and recorded as a percentage.
LDL cholesterol 1, 3, 6, 9 and 12 months Low density lipoprotein-cholesterol level was collected from medical records and recorded as mg/dL
Triglyceride 1, 3, 6, 9 and 12 months Triglyceride level was collected from medical records and recorded as mg/dL.
Body mass index 1, 3, 6, 9 and 12 months Body mass index (BMI) was collected from medical records and recorded as kg/m2
- Secondary Outcome Measures
Name Time Method Drug Related Problem 1 year Determination of drug-related problems (DRP) using Pharmaceutical Care Network Europe (PCNE) Version 9.1. The basic classification has 3 primary domains for problems, 9 primary domains for causes and 5 primary domains for Planned Interventions, 3 primary domains for level of acceptance (of interventions) and 4 primary domains for the Status of the problem.
The National Institutes of Health Stroke Scale 24 hours before discharge, 3, 6, 9 and 12 months The National Institutes of Health Stroke Scale, or NIH Stroke Scale (NIHSS), is a tool used by healthcare providers to objectively quantify the impairment caused by a stroke and aid in planning post-acute care disposition.
Measuring Quality of Life 3, 6 and 12 months The patients' quality of life was evaluated using the Stroke-Specific Quality of Life Scale (SSQOL), and the total quality of life score was calculated, a higher score indicates that the patient has a better quality of life.
Stroke Recurrence 1 year Stroke recurrence (radiologically and clinically confirmed) within 1 year
Trial Locations
- Locations (1)
Marmara University Pendik Research and Training Hospital
🇹🇷Istanbul, Turkey