A comparative study of safety, efficacy and quality of life outcomes of duloxetine with desvenlafaxine in adult patients of diabetic peripheral neuropathy : A Randomized Controlled Academic Trial.
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- A comparative study of safety, efficacy, quality of life outcomes of duloxetine with desvenlafaxine in adult patients of diabetic peripheral neuropathy.
研究概览
简要总结
Diabetic peripheral neuropathy is a chronic complication of diabetes mellitus, primarily involving the peripheral sensory nerves, and it presents with symptoms such as pain, tingling, burning sensations and numbness in the extremities. These symptoms significantly increase the risk of foot ulcers and lower limb amputations.
We will be comparing among two drug regimens, duloxetine and desvenlafaxine in the treatment of diabetic peripheral neuropathy in adult patients.
Publications will be done using the data and results obtained during the study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Adult patients willing to give written informed consent and are diagnosed with diabetic peripheral neuropathy will be included.
排除标准
- •Less than 18 years of age
- •Pregnant and lactating women
- •Patients diagnosed with epilepsy
- •Chronic alcohol consumers
- •Participants with neuropathy due to other causes like vitamin B12 deficiency, thyroid dysfunction, occupational exposure to heavy metals like arsenic, lead, etc.
- •Patients allergic or with known contraindications to either duloxetine or desvenlafaxine.
结局指标
主要结局
A comparative study of safety, efficacy, quality of life outcomes of duloxetine with desvenlafaxine in adult patients of diabetic peripheral neuropathy.
时间窗: Baseline, 4 weeks, 8 weeks, 12 weeks
次要结局
未报告次要终点
研究者
Prarthana Deori
Dr. Rajendra Prasad Government Medical College, Kangra at Tanda