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临床试验/NCT00512382
NCT00512382已完成不适用

The Nature of Reflux-respiratory Symptoms Association in Difficult to Treat Asthmatic/Wheezing Babies Using Impedance and Wheezy Monitoring

Wolfson Medical Center1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2007年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
15
试验地点
1

研究概览

简要总结

GER and respiratory symptoms are both common phenomenon in children. Both can coexist in the same patient by chance alone. Research reveals increased incidence for both to coexist leading to suspect a temporal association and possible causality. Therefore we conducted an observational study To determine the primary cause (RS or GER)using for the first time both PH-Impedance as measurements of GER and Wheezy monitoring (WEEM) that records simultaneously wheeze and cough noises. Both modalities will be recorded for 12-24 hours. If GER precedes cough/wheeze recordings it points to GER being the possible precipitating factor and vice versa.

详细描述

GER and respiratory symptoms are both common phenomenon in children. Both can coexist in the same patient by chance alone. Research reveals increased incidence for both to coexist leading to suspect a temporal association and possible causality. Therefore we conducted an observational study To determine the primary cause (RS or GER)using for the first time both PH-Impedance as measurements of GER and Wheezy monitoring (WEEM) that records simultaneously wheeze and cough noises. Both modalities will be recorded for 12-24 hours. If GER precedes cough/wheeze recordings it points to GER being the possible precipitating factor.However, If cough/wheeze precedes GER recordings it points to cough/wheeze being the possible precipitating factor. The recordings will be investigated 1 minute before and one minute after each event.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
1 Month 至 18 Months(Child)
性别
All
接受健康志愿者

入选标准

  • Children 1 month - 18 years old
  • Difficult to treat asthma
  • Difficult to treat cough
  • Difficult to treat other respiratory symptoms

排除标准

  • Children on artificial ventilation
  • Children not compliant with PH-Metria and/or WEEM

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Avigdor Mandelberg

Director, Pediatric Pulmonry Unit

Wolfson Medical Center

研究点 (1)

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