Patient-ventilator Asynchrony During Noninvasive Ventilation Assessed Using Diaphragm Ultrasonography
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Diaphragm
- Sponsor
- Centre Hospitalier Saint Joseph Saint Luc de Lyon
- Enrollment
- 15
- Locations
- 1
- Primary Endpoint
- Asynchronies detection with diaphragm ultrasonography
- Last Updated
- 9 years ago
Overview
Brief Summary
Fifteen healthy subjects under non-invasive ventilation will be have a recording of surface electromyogram, measurements of airway flows and pressures as well as a continuous ultrasound. The provocation of leaks on the Ventilation circuit and expiratory trigger modulation will generate a number of asynchronies between the subject and the respirator.
These records will help to assess the agreement between the detection of asynchronies using electromyography of the respiratory muscles (technique of reference) and the diaphragmatic echography. We will also compare the respective performance of two techniques of diaphragmatic exploration (excursion and thickening of the diaphragm). A sensitivity of Ultrasound technique of at least 90% will be interpreted as a satisfactory index of concordance.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Healthy volunteer (male or female)
- •Free and Informed Consent
Exclusion Criteria
- •Known pregnancy, parturient or nursing mother
- •Minor under 18 years of age
- •Major incapable
- •Non-affiliation to the social security scheme
- •Any history of respiratory pathology
Outcomes
Primary Outcomes
Asynchronies detection with diaphragm ultrasonography
Time Frame: thirty minutes
Evaluation of the agreement between asynchronous subject-ventilator detection using diaphragm ultrasonography and detecting the same events in using the electromyogram of the respiratory muscles (as a reference technique.