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Clinical Trials/NCT03683472
NCT03683472
Completed
Not Applicable

Developing a Novel Digital Therapeutic for the Treatment of Generalized Anxiety Disorder

MindSciences, Inc.1 site in 1 country65 target enrollmentMay 20, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Anxiety Disorders
Sponsor
MindSciences, Inc.
Enrollment
65
Locations
1
Primary Endpoint
Change in worry
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The investigators propose to develop and adapt Unwinding Anxiety phone app specifically for individuals with generalized anxiety disorder.

Detailed Description

The study aims are to (1) develop and refine Unwinding Anxiety for individuals with generalized anxiety disorder, (2) determine user engagement and acceptability as well as measure effect sizes of the program vs. treatment as usual, and (3) preliminarily test mechanisms of action. The knowledge gained will set the stage for a number of future studies related to further elucidating the mechanisms of mindfulness, and the clinical efficacy and utility of this type of training delivered via digital therapeutics in general. Specifically, this study will provide necessary variances for powering larger phase 2 studies.

Registry
clinicaltrials.gov
Start Date
May 20, 2019
End Date
October 17, 2019
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Judson Brewer

Director of Research & Innovation

Brown University

Eligibility Criteria

Inclusion Criteria

  • Owns a smart phone
  • GAD - 7 is equal to or greater than 10

Exclusion Criteria

  • If using psychotropic medication - not on a stable dosage for at least 6 weeks
  • Medical disorder of the severity that would interfere with ability to participate
  • Not being fluent in English (due to instructions provided in English)
  • As needed use (i.e. prn) of benzodiazepines
  • Psychotic disorder,
  • Previous MT (e.g. MBSR, other Claritas MindSciences training programs).

Outcomes

Primary Outcomes

Change in worry

Time Frame: Baseline, two months

Penn State Worry Questionnaire (PSWQ)

UA Program engagement

Time Frame: Two months

Number of modules completed

Secondary Outcomes

  • UA Program Acceptability(Two months)
  • Change in non-reactivity & awareness(Baseline, two months)

Study Sites (1)

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