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A Clinical Study to Evaluate the Safety and Efficacy of Capsule Outflo in Patients with Benign Prostatic Hyperplasia

Phase 2
Completed
Conditions
Health Condition 1: null- Benign Prostatic Hyperplasia
Registration Number
CTRI/2012/10/003049
Lead Sponsor
Sahajanand Life Sciences Private Limited
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
75
Inclusion Criteria

•Male patients with aged >=40

•New patients diagnosed with BPH, naïve to any other treatments for BPH

•Patients with International Prostate Symptom Score (IPSS) greater than 7 and less than 18

•Patients with Prostate volume less than 40 cc

•Patients with Qmax of 8-12 ml/sec

•Patients with PVUR less than 200 ml

•Patients willing to give written informed consent and willing to follow up

Exclusion Criteria

•Patients with prostatic cancer; neurogenic bladder; bladder cancer; bladder stones; urethral strictures; neurological conditions that might interfere with normal voiding

•Symptomatic coronary arterial disease, stroke, and cardiovascular events

•Current treatment with systemic corticosteroids or herbal (alternative) medicines

•Patients with abnormal renal and hepatic function

•Any significant disease or disorder that may jeopardize the safety of the subject

•Patients with drug and alcohol abuse

•Any psychiatric disorder

•Patients who have participated in any clinical trial in the past 3 months

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in International Prostate Symptom Score (IPSS) <br/ ><br> <br/ ><br>Change in Uroloflowmetry parametersTimepoint: Change in International Prostate Symptom Score (IPSS)(baseline - 1 month - 2 months - 3months) <br/ ><br> <br/ ><br>Change in Uroflowmetry parameters (baseline - 1 month - 2 months - 3months)
Secondary Outcome Measures
NameTimeMethod
Change in Prostate VolumeTimepoint: Baseline - End of Study
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