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Clinical Trials/NCT05822648
NCT05822648
Completed
Not Applicable

Evaluating a Brief Type 2 Diabetes Prevention Program With Greater Scalability

Stanford University1 site in 1 country62 target enrollmentApril 15, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Type 2 Diabetes
Sponsor
Stanford University
Enrollment
62
Locations
1
Primary Endpoint
Body Mass Index (BMI) - Post-Test
Status
Completed
Last Updated
last year

Overview

Brief Summary

This study aims to test the effectiveness of a Type 2 Diabetes (T2D) prevention program for individuals who have been diagnosed with prediabetes compared to a T2D educational control group. Project health is an obesity prevention program and has produced a 42% to 53% reduction in future onset of overweight/obesity and also produced greater reductions in negative affect compared to assessment-only controls that persisted. Project Health has been adapted to prevent onset of T2D among individuals with prediabetes. The study aims to test the effectiveness of Project Health at reducing BMI, HbA1c levels, increase physical activity and improve glucose control.

Registry
clinicaltrials.gov
Start Date
April 15, 2023
End Date
April 22, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Eric Stice

Professor

Stanford University

Eligibility Criteria

Inclusion Criteria

  • Between the ages of 18 and 65
  • Overweight (BMI between 25 and 40 kg/m2)
  • Diagnosed with prediabetes, defined as having elevated HbA1c (5.7-6.4%).

Exclusion Criteria

  • Not between the ages of 18 and 65
  • Not overweight (BMI between 25 and 40 kg/m2)
  • Not diagnosed with prediabetes, defined as having elevated HbA1c (5.7-6.4%).

Outcomes

Primary Outcomes

Body Mass Index (BMI) - Post-Test

Time Frame: post-test (immediately after completion of 6 week intervention)

BMI will be assessed at post-test to see which intervention produced greater reductions in BMI

Body Mass Index (BMI) - 3-Month Follow-Up

Time Frame: 3-month follow-up

BMI will be assessed at 3-month follow-up to see which intervention produced greater reductions in BMI

HbA1c at 3-month Follow-up

Time Frame: 3-month follow-up

Participants will complete an HbA1c test at 3-month follow-up to determine their pre-diabetes status

Fasting Plasma Glucose

Time Frame: 3-month follow-up

Participants will complete a fasting glucose test at 3-month follow-up to determine their pre-diabetes status

Percent Body Fat - Post-Test

Time Frame: post-test (immediately after completion of 6 week intervention)

Percent Body Fat - 3-Month Follow-Up

Time Frame: 3-month follow-up

Percent Lean Body Mass - Post-Test

Time Frame: post-test (immediately after completion of 6 week intervention)

Percent Lean Body Mass - 3-Month Follow-Up

Time Frame: 3-month follow-up

Study Sites (1)

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