MedPath

Evaluation of the Latella Knee Implant System for Medial Osteoarthritis Pain Reduction (Latella-2 Study)

Not Applicable
Terminated
Conditions
Osteoarthritis
Registration Number
NCT02343705
Lead Sponsor
Cotera, Inc.
Brief Summary

The objective of the Latella-2 study is to demonstrate the safety and efficacy of the Latella Knee Implant System for the reduction of medial osteoarthritis knee pain.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
67
Inclusion Criteria
  • History of pain due to medial osteoarthritis
  • Qualifying baseline pain scores
  • Kellgren-Lawrence Grades 2-3
Exclusion Criteria
  • Osteoporosis
  • Rheumatoid arthritis
  • Joint instability
  • Metal ion allergy
  • Permanent implant in or around the knee joint
  • Prior anterior cruciate ligament reconstruction

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Primary Endpoint: Efficacy assessed by KOOS pain score at 6 months after treatment with the Latella Implant6 Months
Primary Endpoint: Safety assessed by surgical re-intervention rate following implantation of the Latella device6 Months
Secondary Outcome Measures
NameTimeMethod
Device and procedure complication rates6, 12 and 24 months
Changes in knee outcome measures (KOOS, IKDC, NRS)6, 12 and 24 months

Trial Locations

Locations (12)

Slotervaart Hospital

🇳🇱

Amsterdam, Netherlands

Amphia Ziekenhuis

🇳🇱

Breda, Netherlands

St. Anna Hospital

🇳🇱

Geldrop, Netherlands

University Hospital Maastricht

🇳🇱

Maastricht, Netherlands

Isala

🇳🇱

Zwolle, Netherlands

Hospital Clinic

🇪🇸

Barcelona, Spain

Hospital Vall d'Hebron

🇪🇸

Barcelona, Spain

Hospital Clinico San Carlos

🇪🇸

Madrid, Spain

Hospital Fundacion Jimenez Diaz

🇪🇸

Madrid, Spain

Royal London Hospital

🇬🇧

London, United Kingdom

Scroll for more (2 remaining)
Slotervaart Hospital
🇳🇱Amsterdam, Netherlands

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.