Phase II study of docetaxel and S-1 as neoadjuvant chemotherapy + gastrectomy for cStage IIIa-IIIb(IV) resectable gastric cancer
Phase 2
- Conditions
- clinical stage IIIa-IIIb(IV) gastric cancer
- Registration Number
- JPRN-UMIN000000875
- Lead Sponsor
- Dept. of Surgery and Science, Kyushu University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Not provided
Exclusion Criteria
A history of other malignancies within the last 5 years except for adequately treated non-melanoma skin cancer or carcinoma in situ of the cervix, patients contraindicated to S-1, A history of severe drug hypersensitivity, Uncontrolled medical conditions , Documented or suspected infection, Patients requiring treatment with corticosteroids except for pre-medication, Hepatitis B or C, patients with diarrhea, Pregnant or lactating women and women of child bearing potential not using contraception, Severe psychiatric disorders, Severe edema, Grade 2 or grater peripheral neuropathy, HIV positive, patients judged by the investigator as unfit to be enrolled in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pathological response
- Secondary Outcome Measures
Name Time Method Response rate of neoadjuvant chemotherapy Treatment completion rate Complete resection rate 3 year relapse free survival 3 year overall survival Adverse events