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Clinical Trials/NCT05107297
NCT05107297
Not yet recruiting
Not Applicable

Comparison of National Early Warning Score (NEWS) & Sepsis Patient Evaluation in the Emergency Department (SPEED) for The Early Identification of Sepsis in the Emergency Department

Assiut University0 sites120 target enrollmentNovember 1, 2021
ConditionsSepsis Scores

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Sepsis Scores
Sponsor
Assiut University
Enrollment
120
Primary Endpoint
Mortality .
Status
Not yet recruiting
Last Updated
4 years ago

Overview

Brief Summary

The aim of the study was to identify co-variates associated with 30-day mortality in septic patients admitted to the emergency department in order to improve morbidity & mortality as a sequence of sepsis in Assiut & Suez Canal Universities by comparing both scores by utilizing parameters that are readily available .

Detailed Description

There are a relatively large number of conditions where urgent intervention is required in order to secure the best outcome for the patient. Examples include sepsis, myocardial infarction (MI). Clinical diagnosis of some of these conditions is not always straightforward, but a common theme is that many present with deranged physiology and vital signs. Implementation of an early warning score on arrival at hospital has helped to identify seriously ill patients . There is a high mortality rate associated with severe infection at all ages Sepsis occurs when life-threatening organ dysfunction is associated with infection. What is a national early warning score (NEWS)? The following six simple physiological parameters are included in the scoring system: respiratory rate, oxygen saturation, temperature; the normal human body temperature range is typically stated as 36.5-37 °C( ), systolic blood pressure, pulse rate \& level of consciousness. What is a sepsis patient evaluation in the emergency department (SPEED)? The following simple clinical, physiological and laboratory parameters are included in the scoring system : hypotension (systolic pressure \<90 mmHg) hypothermia (body temperature \<36.0°C) , hypoxemia (pulse oximetry \<90%), low hematocrit (hematocrit \<0.38), Acidosis (blood PH \< 7.35), elevated blood lactate \>2.4 mmol/L \& source of infection as pneumonia.

Registry
clinicaltrials.gov
Start Date
November 1, 2021
End Date
February 1, 2025
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mostafa Hassan Mostafa Abdellah

resident

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Age of 18 - 80 years.
  • Patients of both genders.

Exclusion Criteria

  • Patient refusal .
  • Accepts Healthy Volunteers .
  • Aged below 18 years

Outcomes

Primary Outcomes

Mortality .

Time Frame: 30 days

Mortality during the 30 day follow-up.

Secondary Outcomes

  • Readmission in the ED .(Hour 72, Day 30)
  • ICU/HDU admission .(Day 0)
  • Hospital admission .(Day 0)

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