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临床试验/NCT06419517
NCT06419517
已完成
不适用

Efficacy of PFMT and sEMG-triggered Electrostimulation in Treating the Very Weak Pelvic Floor: a Randomized Clinical Trial

Azienda Unita Sanitaria Locale di Piacenza1 个研究点 分布在 1 个国家目标入组 50 人2024年5月17日

概览

阶段
不适用
干预措施
Pelvic Floor Muscle Training
疾病 / 适应症
Pelvic Floor Muscle Weakness
发起方
Azienda Unita Sanitaria Locale di Piacenza
入组人数
50
试验地点
1
主要终点
Pelvic Floor Muscles (PFM) Strength
状态
已完成
最后更新
2个月前

概览

简要总结

This research will determine 1) whether the very weak pelvic floor can be improved with surface electromyography (s-EMG)-triggered electrostimulation added to pelvic floor muscle training and 2) whether sEMG-triggered electrostimulation added to pelvic floor muscle training can reduce leakage in Stress Urinary Incontinence (SUI)

详细描述

Among women with pelvic floor dysfunction, it has long been known that PFM training is the first-line therapy for stress incontinence. One of the difficulties that clinicians often find upon examination is that many women present a very weak pelvic floor and are unable to contract their PFM. There is overwhelming evidence to show that conservative treatment in the form of pelvic muscle exercises (and to a lesser degree, electrotherapy, and vaginal weight therapy) is effective in the treatment of stress urinary incontinence. To date, there is some evidence to support the use of electrical stimulation for stress urinary incontinence in women, but we are still very uncertain about the full potential of this treatment because of the low quality of the existing evidence.

注册库
clinicaltrials.gov
开始日期
2024年5月17日
结束日期
2025年12月31日
最后更新
2个月前
研究类型
Interventional
研究设计
Parallel
性别
Female

研究者

发起方
Azienda Unita Sanitaria Locale di Piacenza
责任方
Principal Investigator
主要研究者

DR. GIANFRANCO LAMBERTI

Director, Rehabilitative Medicine Department

Azienda Unita Sanitaria Locale di Piacenza

入排标准

入选标准

  • • Adult women (18 years old - 50 years old), with a Modified Oxford Score, determined by digital palpation, of 0 - 1, complaining leakage episode occurring more than once a week.
  • Between six and eighteen months after childbirth
  • Willing and able to be compliant with pelvic floor muscle exercise intervention (standard of care) for 12 weeks and to log compliance
  • Willing and able to undergo an extensive physical function evaluation

排除标准

  • • pregnancy
  • severe neurological disease (Multiple Sclerosis, Parkinson's disease, spinal cord injury, major stroke or neuromuscular junction diseases)
  • previous operation for cancer or radiotherapy in the lower abdomen
  • Prior surgical intervention for urinary incontinence within the past 12 months
  • Hysterectomy within 12 months
  • voiding dysfunction
  • pelvic pain
  • severe prolapse (≥ grade 3)
  • recurrent urinary tract infection
  • pelvic or disseminated malignancies

研究组 & 干预措施

Supervised Pelvic Floor Muscle Training + EMG-triggered ES

Group A (supervised PFMT + EMG-triggered ES) Supervised Pelvic Floor Muscle Training Twenty sessions will be applied, 2 per week for ten weeks Stimulation parameters: Duration: 15 min Electrode placement: vaginal probe Frequency: 50 Hz. - Pulse width 250 microseconds Intensity: to motor response (activation of PFM) Number of sessions: 20 Ramp up/down: 1 sec.

干预措施: Pelvic Floor Muscle Training

Supervised Pelvic Floor Muscle Training + EMG-triggered ES

Group A (supervised PFMT + EMG-triggered ES) Supervised Pelvic Floor Muscle Training Twenty sessions will be applied, 2 per week for ten weeks Stimulation parameters: Duration: 15 min Electrode placement: vaginal probe Frequency: 50 Hz. - Pulse width 250 microseconds Intensity: to motor response (activation of PFM) Number of sessions: 20 Ramp up/down: 1 sec.

干预措施: EMG-triggered ES

Supervised PFMT + sham EMG-triggered ES)

Group B: Supervised PFMT + sham EMG-triggered ES) Supervised Pelvic Floor Muscle Training Twenty sessions will be applied, 2 per week for ten weeks Stimulation parameters: Duration: 15 min Electrode placement: vaginal probe model xx Frequency: 2 Hz. - Pulse width 10 microseconds Intensity: to sensory response Number of sessions: 20 Ramp up/down: 1 sec.

干预措施: Pelvic Floor Muscle Training

结局指标

主要结局

Pelvic Floor Muscles (PFM) Strength

时间窗: Baseline, four weeks, 6 and 12 months follow-up

PFM strength by digital palpation done in the lithotomy position

次要结局

  • International Consultation on Incontinence Questionnaire-Short Form(ICIQ-SF)(Baseline, four weeks, 6 and 12 months follow-up)
  • Frequency/volume chart(Baseline, four weeks, 6 and 12 months follow-up)

研究点 (1)

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