PACTR201802003063273尚未招募未知
Sulphadoxine/Pyrimethamine and Proguanil for malaria prophylaxis in Sickle Cell pregnancy: A Randomized Controlled Trial (SPICKLE TRIAL)
EDCTP0 个研究点目标入组 248 人开始时间: 2018年2月7日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 248
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 15 Year(s) 至 49 Year(s)（—）
- 性别
- Female
入选标准
- •¿Pregnant women of all gravidity confirmed as having HbSS genotype.
- •¿Screened after 16 weeks or onset of quickening, both aparasitaemic and parasitaemic at first enrolment.
- •¿Must give informed written consent.
排除标准
- •¿Known adverse drug reaction to any of the two medications (Sulphadoxine/Pyrimethamine and Proguanil).
- •¿Co-existing medical disorders that may alter immunity such as diabetes mellitus (DM) and human immunodeficiency virus infection (HIV).
- •¿Multiple gestations.
- •¿Presence of severe clinical malaria at booking.
- •¿Less than 16 weeks gestational age for Sulphadoxine/Pyrimethamine (SP) group.
- •¿Use of antimalarials within the last one week prior to booking.
- •¿Refusal to give informed written consent.
研究者
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