Use of Quantra® System in Clinical Practice to Improve Management of Post-partum Haemorrhage : a Prospective Study
Trial Snapshot
- Phase
- Not Applicable
- Enrollment
- 60
- Primary Endpoint
- Comparison of delay in obtaining Quantra Fibrinogen Clot Stiffness result to standard fibrinogen level result
Study Overview
Brief Summary
Post partum haemorrhage is a concerning situation in maternity wards, though it is not the first cause of maternal mortality anymore.
It has been already shown that low fibrinogen level is a major predictive factor of massive bleeding after delivery.
In this situation, the early knowledge of fibrinogen level could enhance care of women experiencing post partum haemorrhage.
In a cohort of women suffering from post partum haemorrhage, this study will evaluate whether assessing fibrinogen level would be faster using the Quantra® system than the standard coagulation test.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Women ≥ 18 years old Experiencing post partum haemorrhage ≥ 500 mL Within 24 hours after delivery
Exclusion Criteria
- •Previous anemia ≤ 7g/dL
- •Known bleeding disorders
- •Ongoing antiplatelets treatment
- •Ongoing anticoagulant treatment
Outcomes
Primary Outcomes
Comparison of delay in obtaining Quantra Fibrinogen Clot Stiffness result to standard fibrinogen level result
Time Frame: When post partum haemorrhage occurred, within 24 hours after delivery
Comparison of delay in obtaining Quantra Fibrinogen Clot Stiffness result to standard fibrinogen level result
Secondary Outcomes
- Rate of satisfaction of anesthetist in charge of patient assessed by Lickert scale(When post partum haemorrhage occurred, within 24 hours after delivery)
- Comparison of Quantra Clot Time result to Standard Kaolin Clotting time result(When post partum haemorrhage occurred, within 24 hours after delivery)
- Comparison of level of fibrinogen assessed by Quantra Fibrinogen Clot Stiffness to level of fibrinogen assessed by standard coagulation test(When post partum haemorrhage occurred, within 24 hours after delivery)
- Comparison of Platelet Clot Stiffness result to standard platelet count result(When post partum haemorrhage occurred, within 24 hours after delivery)
Investigators
GRENIE
Doctor
University Hospital, Montpellier