Influence of pre-operative vaccination on immune response and post-operative infection rate

Completed

• Conditions: pper aerodigestive tract cancer undergoing surgery; Cancer; Digestive tract cancer

• Registration Number: ISRCTN16108096
• Lead Sponsor: Charité - University Medicine Berlin (Charité - Universitätsmedizin Berlin) (Germany)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-01-29
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

Tumour resection of upper aerodigestive tract.

Exclusion Criteria

Initial information at time of registration:
1. No consent
2. Under 18 years
3. Liver insufficiency (more than Child B)
4. Acute Coronary Syndrome (less than 8 weeks)
5. Human Immunodeficiency Virus (HIV) positive
6. Corticosteriodal treatment
7. After organ transplantation
8. Current infection
9. Pregnancy

Added as of 30/03/2009:
10. Diabetes mellitus
11. Status post splenectomy
12. Protein deficiency
13. Known allergy to components of the vaccine
14. Immunosuppression

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Influence of pre-operative vaccination on immune response.

Secondary Outcome Measures

Name	Time	Method
Influence of pre-operative vaccination post-operative infection rate.