A comparative study on three different combinations of ketofol for induction of general anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Induction time, hemodynamic response to induction of general anesthesia, adverse outcome if ,any
研究概览
简要总结
This study is to compare the hemodynamic response after induction of general anesthesia with different combinations of ketofol. One group will receive intravenous ketamine @ dose of 1mg/ kg and propofol @ 1mg/ kg. Another group will receive 1.33 mg/ kg of propofol and 0.66 mg/kg of ketamine. And the third group will receive 1.5 mg/ kg of propofol and 0.5mg/ kg of ketamine. Hemodynamic parameters will be recorded just after induction till 5 minutes after induction for every one minute
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with ASA I or II Patients willing to give consent Patients of age group 18 to 60 years undergoing elective surgery under general anesthesia.
排除标准
- •Patients refusal Anticipated difficult airway Patients with diabetes or hypertension Pregnant or breastfeeding mother Patients with respiratory, cardiac ,neurological,renal or liver disease Patients with known allergy to drugs used for induction of anesthesia Psychiatric patients.
结局指标
主要结局
Induction time, hemodynamic response to induction of general anesthesia, adverse outcome if ,any
时间窗: From the start of induction till loss of verbal command, hemodynamic parameters: baseline,just after induction, 1 minute, 2 minutes, 3 minutes, 4 minutes and 5 minutes after induction. adverse effects if any in post operative care unit
次要结局
未报告次要终点