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Clinical Trials/NCT06498193
NCT06498193
Active, not recruiting
Not Applicable

A Comparative Study of Cancer-related Fatigue Among Patients Receiving Home-based Palliative Care and Hospice-shared Care

National Taipei University of Nursing and Health Sciences1 site in 1 country120 target enrollmentJanuary 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
to Investigate the Level of Fatigue Among Terminal Cancer Patients Receiving Home-based Hospice Care
Sponsor
National Taipei University of Nursing and Health Sciences
Enrollment
120
Locations
1
Primary Endpoint
comparing CRF scores at baseline with those after one week,
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

Cancer-related fatigue, which significantly impacts the quality of life, is prevalent among patients with terminal cancer. The experiences of fatigue, its associated needs, and the strategies for managing it are closely linked to the individual uniqueness, cultural background, and resource availability of terminal cancer patients.

Detailed Description

Fatigue is defined as any perceived or actual physical or mental tiredness that adversely affects the quality of life \[7,8\]. The multifaceted nature of fatigue means it manifests in various forms, including physical cognitive, and emotional. Fatigue may involve chronic exhaustion and reduced mobility that cannot be relieved by rest \[9,10\]. CRF is associated with cancer progression and treatment, presenting it as a painful, persistent, and subjective sensation involving physical, emotional, and cognitive tiredness or exhaustion. CRF disproportionately affects physical activities and impairs executive functions in daily life \[10,11\]. Factors contributing to CRF include cancer itself, treatment side effects, psychological factors such as personality traits (e.g., levels of optimism, anxiety, or depression), comorbid physical conditions, iatrogenic comorbidities, and lifestyle factors (e.g., physical activity levels) \[10-12\]. From the perspective of individual patients, fatigue frequently coexists with symptom clusters, such as insomnia, low mood or depression, or pain, collectively resulting in reduced daily functioning and diminished quality of life \[13\]. Various non-pharmaceutical interventions have demonstrated effectiveness in addressing CRF, including physical activity, mind-body approaches, and psychosocial interventions \[9,14,15\]. Therefore, this study aims to investigate the level of fatigue among terminal cancer patients receiving home-based hospice care, hospital-based hospice care, and hospice-shared care. The anticipated results may facilitate the enhancement of CRF management strategies

Registry
clinicaltrials.gov
Start Date
January 1, 2024
End Date
September 30, 2024
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Pei-Hung Liao

Department of Nursing

National Taipei University of Nursing and Health Sciences

Eligibility Criteria

Inclusion Criteria

  • (i) patients aged 20 years and above proficient in Mandarin and/or Taiwanese and willing to participate in the study; (ii) patients deemed ineligible for curative treatments by oncologists or cancer-related specialists; (iii) patients with an Eastern Cooperative Oncology Group Scale (ECOG) score of 2 or above suitable for hospice care; and (iv) patients who signed a letter of intent for hospice care,

Exclusion Criteria

  • preference on their National Health Insurance card, or signed a letter of intent for do-not-resuscitate. Patients deemed too frail

Outcomes

Primary Outcomes

comparing CRF scores at baseline with those after one week,

Time Frame: 1 week

The BFI survey was utilized to promptly assess CRF severity and its impact on daily functioning.

Study Sites (1)

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