NCT01770938已完成不适用
Effects of Phototherapy by Low-level Light-emitting Diode Therapy (LEDT) on Clinical, Biochemical, Biomechanical, Histologic and Genetic Responses of Muscle Performance of Young Males Submitted to Physical Strength Training
Universidade Federal de Sao Carlos2 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2012年5月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 32
- 试验地点
- 2
- 主要终点
- Modulations on muscle gene expression by RT-PCR
研究概览
简要总结
Muscle performance is largely influenced by modulations in gene expressions of muscle tissue. In this context, light-emitting diode therapy (LEDT) has been used to improve muscle performance in experimental models and human researches. Thereby, the investigators examined modulations in gene expression of muscle tissue as well as biochemical, biomechanic and histologic adaptations influenced by exercise associated to LEDT.
详细描述
This study assessed muscle performance in isokinetic dynamometry and led press device, gene expression by RT-PCR, lactate, creatine kinase and morphology of muscle tissue by immunohistochemical analysis
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 28 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •healthy males aged between 18 and 28 years with a body mass index (BMI) equal to or less than 26 kg/m2,
- •moderated pattern of physical activity
排除标准
- •previous injury to the femoral quadriceps or hamstring muscles (within 6 months prior to study),
- •osseous or articular disorder in the lower limbs,
- •cardiovascular system disorders,
- •systemic disease, and
- •taking prescription medicines or using dietary supplements such as muscle mass builders.
结局指标
主要结局
Modulations on muscle gene expression by RT-PCR
时间窗: 12 weeks
次要结局
- Gene expression(12 weeks)
- Muscle performance in leg press device(12 weeks)
- Muscle performance in leg extension device(12 weeks)
- Muscle performance in isokinetic dynamometer(12 weeks)
研究者
Cleber Ferraresi
MSc
Universidade Federal de Sao Carlos
研究点 (2)
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