The effect of intravenous selenium on stress oxidative in Acute Respiratory Distress Syndrome (ARDS) patients in intensive care units

Not Applicable

Recruiting

• Conditions: Acute respiratory distress syndrome.; Adult respiratory distress syndrome

• Registration Number: IRCT201706172582N17
• Lead Sponsor: Vice chancellor for research, Tabriz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Major inclusion criteria: patients above 18 years; asymmetric and diffused involvemnet of lungs in chest X-ray; lung involvement less than a week; proportion of arterial oxygen pressure (Pao2) to Fio2 more than 200; Exclusion criteria: hypersensitivity to Selenium; pregnancy and lactation; renal failure

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oxidative stress status(gluthatione peroxidase). Timepoint: One day before the intervention. Seven days after intervention. Fourteen days after the intervention. Method of measurement: using FRAP and TRAP kits.;Ventilation free days. Timepoint: number of days that patients do not require mechanical ventilation, within the 14 days of study period. Method of measurement: with counting the ventilation free days and recording them in forms.

Secondary Outcome Measures

Name	Time	Method
Vasopressor free days. Timepoint: number of days that patients do not require vasopressor administration, within the 14 days of study period. Method of measurement: with counting vasopressor free days and recording them in forms.