Effects of Green Tea Supplementation on Cardiometabolic Parameters
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Systolic blood pressure
研究概览
简要总结
Cardiovascular disease, type 2 diabetes mellitus and associated diseases combined are the leading health burden and cause of mortality worldwide; therefore, the necessity for an intervention is paramount. Dietary interventions to improve cardiometabolic health are highly sought after as they possess less risk than pharmacological drugs. It has been postulated that Green tea may be beneficial in improving cardiometabolic outcomes. However, to date, no research has explored this using a placebo randomized intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Between 18 & 65 years
- •Non-smoker
- •BMI < 30
- •Able to give informed consent
排除标准
- •Pregnancy
- •Diabetes or any other metabolic/ uncontrolled hypertensive conditions
- •Food allergies to quercetin
- •Habitual consumption of quercetin
- •Not regularly taking medication or antioxidant supplements
研究组 & 干预措施
Green tea
Green tea tablets 1000mg 1 x per day
干预措施: Green tea (Dietary Supplement)
Placebo
Placebo control 1 x blinded placebo tablet per day
干预措施: Placebo (Other)
结局指标
主要结局
Systolic blood pressure
时间窗: 20 days
Systolic blood pressure - measured using a digital blood pressure monitor
Systolic blood pressure
时间窗: Baseline
Systolic blood pressure - measured using a digital blood pressure monitor
次要结局
- Percent bodyfat(20 days)
- Diastolic blood pressure(20 days)
- Blood triglycerides(20 days)
- Blood cholesterol (Total, HDL & LDL)(20 days)
- Beck Depression Inventory(20 days)
- Epworth Sleepiness Scale(20 days)
- Waist to hip ratio(20 days)
- Blood glucose(20 days)
- Insomnia Severity Index(20 days)
- Triglyceride glucose index(20 days)
- Coop-Wonka chart(20 days)
- State Trait Anxiety Inventory(20 days)
- Pittsburgh Sleep Quality Index(20 days)
- Diastolic blood pressure(Baseline)
- Percent bodyfat(Baseline)
- Waist to hip ratio(Baseline)
- Blood glucose(Baseline)
- Blood triglycerides(Baseline)
- Triglyceride glucose index(Baseline)
- Blood cholesterol (Total, HDL & LDL)(Baseline)
- Coop-Wonka chart(Baseline)
- Beck Depression Inventory(Baseline)
- State Trait Anxiety Inventory(Baseline)
- Insomnia Severity Index(Baseline)
- Pittsburgh Sleep Quality Index(Baseline)
- Epworth Sleepiness Scale(Baseline)
研究者
Jonathan Sinclair
Professor
University of Central Lancashire