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Clinical Trials/NCT04871009
NCT04871009
Completed
Not Applicable

A Trial of Neurofeedback as an Adjunctive Treatment for Youth in Outpatient Mental Health Settings

University of Rochester2 sites in 1 country40 target enrollmentFebruary 28, 2022
ConditionsTrauma

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Trauma
Sponsor
University of Rochester
Enrollment
40
Locations
2
Primary Endpoint
Mean change in Trauma Symptom Checklist for Young Children (TSCYC)
Status
Completed
Last Updated
3 months ago

Overview

Brief Summary

The purpose of this study is to test the feasibility and effectiveness of a neurofeedback intervention conducted as an adjunctive behavioral health treatment to reduce trauma and affective symptoms in trauma-exposed youth.

Registry
clinicaltrials.gov
Start Date
February 28, 2022
End Date
August 1, 2025
Last Updated
3 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Thomas O'Connor

Professor

University of Rochester

Eligibility Criteria

Inclusion Criteria

  • caregiver-reported exposure to two or more ACE types on the ACE-Q-Child measure.
  • ages of 6-12 years old
  • receiving or eligible to receive trauma-focused cognitive behavior therapy or another type of trauma-focused therapy, as determined by their primary therapist, designated as the TAU condition
  • speaks and reads English
  • (caregivers)
  • own an iPhone, iPad, smartphone, or tablet that is equipped with Bluetooth and uses an Apple or Android operating system that is compatible with the MUSE Calm app and accompanying MUSE wearable neurofeedback device
  • speaks and read English

Exclusion Criteria

  • Child-caregiver dyads will be excluded if
  • the child falls outside of the required age range,
  • has a documented history of epilepsy
  • is currently considered to be at high risk for suicide attempt
  • is currently experiencing psychosis

Outcomes

Primary Outcomes

Mean change in Trauma Symptom Checklist for Young Children (TSCYC)

Time Frame: baseline to 3 months

Children's trauma symptoms will be measured by the Trauma Symptom Checklist for Young Children (TSCYC) at baseline and post-intervention intervals. This caregiver-report measure is developed for children between the ages of 4-12. It consists of 90-items that encompass two reporter validity scales, eight symptom-specific clinical subscales. Answers to individual items are based on a 4-point scale with response options ranging from 1 ("Not at All") to 4 ("Very Often"), and is administered and scored in accordance with manualized instructions. This study will assess trauma symptoms via subscale scores for levels of overall post-traumatic stress, dissociation, post-traumatic intrusion, arousal, and avoidance, and trauma-related aggression. Scale ranges from 90-360 with higher scores indicating worse outcomes.

Mean change in Short Mood and Feelings Questionnaire (SMFQ)

Time Frame: baseline to 3 months

The child-report version of the Short Mood and Feelings Questionnaire (SMFQ)contains 13 items measuring depressive symptom severity over a 2-week period. Each item has 3 response categories: "True" (=2, the item applies to them most of the time), "Sometimes" (=1, the item applies to them sometimes), or "Not True" (=0, the item is not true about them). Scale ranges from 0-26 with higher scores indicating worse outcome.

Mean change in Patient Reported Outcomes Measurement Information System Pediatric Item Bank v2.0 - Anxiety - Short Form 8a (PROMIS)

Time Frame: baseline to 3 months

The child-report version of the Patient Reported Outcomes Measurement Information System Pediatric Item Bank v2.0 - Anxiety - Short Form 8a (PROMIS)measures anxiety symptoms experienced by youth over the past seven days (PROMIS, 2019). The PROMIS (2019) contains 7 items, each with a 5-point Likert scale (1-5) by which youth indicate the frequency that each item applies to them (1=Never, 2=Almost Never, 3=Sometimes, 4=Often, 5=Almost Always). Scales ranges from 1-35 with higher scores indicating worse outcome.

Secondary Outcomes

  • Mean number of sessions per week(3 months)
  • mean length of each session(3 months)
  • Number of caregivers reporting childhood trauma(baseline to 3 months)
  • post traumatic stress disorder (PTSD) Checklist for DSM-5 (PCL-5)(baseline to 3 months)
  • Mean satisfaction with the intervention(3 months)
  • Mean change in Beck Depression Inventory II (BDI-II)(baseline to 3 months)
  • Parental Stress Scale (PSS)(Baseline to 3 months)

Study Sites (2)

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