A clinical trial to study the effects of different exercise intensities on an inflammatory marker named C Reactive Protein

Completed

Conditions: Healthy sedentary individuals who are at risk of developing coronary heart disease.

Registration Number: CTRI/2009/091/001005

Brief Summary: This study is a randomised controlled trial comparing the effect of different exercise intensities on High Sensitivity C Reactive Protein. 92 healthy sedentary volunteers will be recruited and assigned to one of the four groups(control and exercise training with three different exercise intensities). Participants will undergo 8 weeks of exercise intervention or no exercise. The primary outcome measure High Sensitivity C Reactive Protein and secondary outcome measures peak oxygen uptake, waist circumference and Percent bodt fat will be measured at baseline and after 8 weeks of intervention

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 92

Inclusion Criteria

Individuals of both genders who have not participate in a structured exercise program regularlyPlasma CRP value >1mg/L and <10mg/LAged between 18 to 40 years.

Exclusion Criteria

Current illness associated with systemic inflammatory responseHistory of hypertension and diabetesEvidence of cardiovascular disease on physical examination, electrocardiography, treadmill exercise testingCardiovascular medications (including aspirin) / NSAIDs / steroids/ statins/ niacinAny other pulmonary and neuromusculoskeletal impairment that contraindicates exerciseAcute illness during the period of study.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
High Sensitivity C reactive Protein	Pre and post exercise training

Secondary Outcome Measures

Name	Time	Method
Peak Oxygen Uptake, Waist Circumference and Percent Body Fat, Body weight, Total Cholesterol, Triglycerides, LDL, HDL, TC/HDL Ratio, Blood glucose	Pre and Post Exercise training

Trial Locations

Locations (1): Department of Physiotherapy
🇮🇳
Udupi, KARNATAKA, India
Department of Physiotherapy
🇮🇳Udupi, KARNATAKA, India
Fiddy Davis J
Principal investigator
fiddydavis@yahoo.com