Quantitative Analysis of Cell-free Epstein-Barr Virus and Human papilloma virus DNA as a Biomarker in patients with Nasopharyngeal and Oropharyngeal carcinomas: Prospective single-center study
- Conditions
- Neoplasms
- Registration Number
- KCT0006647
- Lead Sponsor
- ational Cancer Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
? Nasopharyngeal carcinoma
- Primary nasopharyngeal carcinoma that has been pathologically confirmed
- No distant metastasis based on PET-CT imaging (T0 to T4, N0 to N3, M0 (AJCC 7th edition))
- Age 18 years or older
- Consented to participate for the study
? Oropharyngeal carcinoma
- Primary oropharyngeal carcinoma that has been pathologically confirmed
- No distant metastasis based on PET-CT imaging (T0 to T4, N0 to N3, M0 (AJCC 7th edition))
- Age 18 years or older
- Metastatic cervical lymph nodes confirmed as squamous cell carcinoma should have p16 immunostaining positive results (TxN+M0)
- Consented to participate for the study
? Other primary cancer diagnosed
? Metastatic cervical lymph node of squamous cell carcinoma that has p16 IHC negative results
? Recurrent or metastatic nasopharyngeal or oropharyngeal carcinoma
? Patients with previous treatment history of RT or chemotherapy for nasopharyngeal or oropharyngeal carcinoma
? Unable for blood sampling
? Refused to participate for the study
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method