Comparison the effect of Propranolol and Topiramate in Pediatric Migraine prophylaxis
Phase 2
- Conditions
- Migraine.Migraine without aura [common migraine]
- Registration Number
- IRCT201009221808N2
- Lead Sponsor
- Research Center of Mazandaran University of Medical Sciences and Health Services
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Inclusion Criteria: 1- Age between 5-15 yr 2- Patient with Common Migraine IHS criteria 3- History of Headache in last 6months 4- No Drug history of Propranolol or Topiromate 5- Discontinuation of other prophylactic drugs one month prior to study 6- At least 2 episode of Migraine Headache in one month.
Exclusion Criteria
1- Contraindications of Propranolol or Topiromate in pre-existing Disease 2- Patient with Epilepsy or Movement Disorders 3- Patient who don’t follow up their Treatment 4- Appearing of drug side effects.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of Migraine Headache episode. Timepoint: Before intervention, 4 & 8 weeks after intervention. Method of measurement: Questionnarie.
- Secondary Outcome Measures
Name Time Method ausea & Vomiting. Timepoint: 4 & 8 weeks after beginning of treatment. Method of measurement: Questionnaire.;Weight loss. Timepoint: 4 & 8 weeks after beginning of treatment. Method of measurement: Questionnaire.;Drowsiness. Timepoint: 4 & 8 weeks after beginning of treatment. Method of measurement: Questionnaire.