Therapeutic Effects of Cryotherapy on Arthrogenic Muscle Inhibition in Patients With Cruciate Ligament Reconstruction

Not Applicable

• Conditions: Anterior Cruciate Ligament Injury
• Interventions: Device: cryotherapy

• Registration Number: NCT01273649
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Anterior cruciate ligament(ACL) injury is one of the most common sport injuries. The major problem after ACL reconstruction or rehabilitation program is quadriceps weakness. Previous studies suggested that cryotherapy and transcutaneous electrical nerve stimulation(TENS) can effectively reduce the arthrogenic muscle inhibition caused by experimental swelling.

Objective:

To exam the effects of 12 weeks cryotherapy and TENS on arthrogenic muscle inhibition in subjects with ACL reconstruction.

Design:

Prospective study.

Subjects:

Male subjects with isolated ACL injury, age between 18\~40 years old are going to receive an ACL reconstruction surgery.

Methods:

Quadriceps activation level, quadriceps peak torque during maximal voluntary contraction and rate of force development are measure at presurgery, 3-month, 6-month after surgery. After surgery, subjects will receive 12 weeks, 3 days/week, training programs included 20 minutes cryotherapy and exercise training with TENS.

Data analysis:

Data will be analyzed using SPSS 13.0 software (SPSS Inc., Chicago, IL). One-way ANOVA will be used to analysis data.

Detailed Description

Examination procedure:

1. Skin preparation and EMG setting.

2. Fill out knee joint function questionnaire.

3. Warmup with a stationary bike.

4. Single hop for distance.

5. MVIC test and EMG recording.

6. Endurance test.

7. Record surface EMG of vastus lateralis, vastus medialis, biceps femoris and semitendinosus during maximal voluntary contraction.

Study Timeline

• Study Start: 2011-01
• Study First Submitted: 2011-01-06
• Study First Submitted QC: 2011-01-07
• Study First Posted: 2011-01-10
• Status Verified: 2014-05
• Last Update Submitted: 2014-05-27
• Last Update Posted: 2014-05-29
• Primary Completion: 2014-09
• Study Completion: 2014-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 30

Inclusion Criteria

• Male subjects with isolated ACL injury, age between 18~40 years old are going to receive an ACL reconstruction surgery.

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Exclusion Criteria

• meniscus lesion, bony fracture and osteochondral lesions

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
ice, rate of force development	cryotherapy	to monitor the long term effect of cryotherapy in rate of force development.

Primary Outcome Measures

Name	Time	Method
Muscle activation	6 months	To provide information of individual muscles for the correlation analyses, parameters of muscle activation, such as the integrated electromyography (EMG) normalized to the maximal M wave, are favored.

Trial Locations

Locations (1)

National Taiwan University; 🇨🇳 Taipei, Taiwan