checking the efficacy of triple fixed dose combination-timolol, brinzolamide and brimonidine in patients with open angle glaucoma and ocular hypertension not responding to dual drug therapy
- Conditions
- Health Condition 1: H401- Open-angle glaucoma
- Registration Number
- CTRI/2024/05/067045
- Lead Sponsor
- I
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1) Patients of either gender aged more than 18 years, baseline IOP more than18mmHg ,with a diagnosis in each eye of either:
2) Ocular hypertension
3) Chronic or primary open angle glaucoma
4) Chronic angle closure glaucoma with patent PI
5) Pseudoexfoliative glaucoma
6) Pigmentary glaucoma
1) Known allergy, contraindication, hypersensitivity, or contraindication to the study medication or any of its components
2) active ocular disease other than glaucoma or OHT (except chronic mild blepharitis, cataract, age-related macular degeneration, or background diabetic retinopathy, which could be enrolled at the discretion of the investigator)
3) recent or anticipated changes in therapy for chronic conditions with agents that could affect IOP
4) corneal abnormalities that could preclude accurate IOP readings with applanation tonometry
5)use of corticosteroids within defined exclusion periods prior to baseline and through the study period
6) incisional surgery or laser procedure within defined exclusion periods prior to baseline
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method checking intraocular pressure on DAY 0, 2nd week, 6th week, 12th weekTimepoint: checking intraocular pressure on DAY 0, 2nd week, 6th week, 12th week
- Secondary Outcome Measures
Name Time Method to check the efficacy and safety of the triple fixed dose combinationTimepoint: to check the efficacy and safety of the triple fixed dose combination