EUCTR2005-001384-60-GB进行中（未招募）1 期
An exploratory, observational cohort study investigating commercially available treatments which may reduce the scab stage of recurrent herpes labialis
GlaxoSmithKline Consumer Healthcare0 个研究点目标入组 36 人开始时间: 2005年6月2日最近更新:
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 36
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
入选标准
- •Aged at least 18 years of age.
- •2)Cold Sore History
- •a.History of recurrent herpes labialis and with at least three recurrences during the 12 months prior to screening visit.
- •b.Must have started treating this cold sore episode with topical Zovirax cream at first signs or symptoms of the lesion.
- •c.Only subjects who have reached the papular/oedematous (stage 2) of their cold sore will be included
- •3)Compliance
- •Understands and is willing, able and likely to comply with all study procedures and restrictions.
- •Demonstrates understanding of the study and willingness to participate as evidenced by voluntary written informed consent and has received a signed and dated copy of the informed consent form.
- •5)General Health
- •Good general health with (in the opinion of the investigator) no clinically significant and relevant abnormalities of medical history.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1)Medical History
- •a.Any evidence of active malignancy, immunodeficient disease, or use of immuno-modifying drugs (e.g. systemic steroids) within 30 days prior to Screening Visit.
- •b.Subject has abnormal skin conditions that occur in the area ordinarily affected by cold sores which might affect the normal course of cold sores (e.g. eczema, psoriasis, albinism or chronic vesiculobullous disorders).
- •c.Subject has a recent history of renal dysfunction or serious hepatic disease.
- •d.Current or previous medical history which may require treatment or make the subject unlikely to finish the study.
- •e.Subjects for whom Zovirax is contra-indicated.
- •f.Subjects presenting with a non-classical cold sore lesion or a significant history of cold sores which abort.
- •2)Prior/ Concomitant Medication
- •a.Subject requires chronic use of analgesics, pain medication or non-steroidal anti-inflammatory agents (NSAIDs).
- •b.Subjects using topical steroids on or near the face within 30 days of Screening Visit.
- •3)Clinical Study/ Experimental Medication
- •a.Participation in another clinical study or receipt of an investigational drug within 30 days of the screening visit.
- •b.Previous participation in this study.
- •a.Recent history (within the last year) of alcohol or other substance abuse.
- •5)Pregnancy
- •a.Females who are pregnant.
- •b.Females of childbearing potential who are not practising an acceptable (in the opinion of the investigator) method of birth control.
- •c.Females who are breast–feeding.
- •6)Allergy/Intolerance
- •Known or suspected intolerance or hypersensitivity to the study materials (or closely related compounds) or any of their stated ingredients i.e. aciclovir, or any related anti-viral drug, or the cream base.
- •7)Personnel
- •An employee of the sponsor or those individuals conducting the study at the study site.
研究者
相似试验
尚未招募
不适用
A prospective, explorative cohort study to identify biomarkers of treatment response in oropharyngeal cancer.Oropharyngeal cancerNL-OMON27421Erasmus MC200
招募中
不适用
A prospective, explorative cohort study to assess the value of an ex vivo radiosensitivity assay as a BIOmarker of treatment Response in Oropharyngeal Cancer (BIO-ROC).throat cancer10027655oropharyngeal cancerNL-OMON52756Erasmus MC, Universitair Medisch Centrum Rotterdam200
进行中（未招募）
不适用
The impact of rotavirus vaccine introduction in SAsevere gastroenteritisInfection - Other infectious diseasesACTRN12611000559910Children, Youth and Women's health Service200
招募中
不适用
A prospective, descriptive cohort study evaluating the prevalence and incidence of exocrine pancreatic insufficiency in patients with pancreatic cancer.NL-OMON35011Academisch Medisch Centrum50
尚未招募
不适用
This is a type of cancer found in elderly patientsCTRI/2022/09/045751Investigator initiated trial