Two Strategies for Methicillin-resistant Staphylococcus Aureus (MRSA) Infection Prevention in Surgical Patients
- Conditions
- MRSA Infection
- Interventions
- Other: Rapid molecular MRSA testBehavioral: Hand hygiene promotion
- Registration Number
- NCT00685867
- Lead Sponsor
- University Hospital, Geneva
- Brief Summary
The study is a two-arm controlled multi-centre trial of two strategies to reduce nosocomial MRSA transmission and infection among surgical patients. Enrolment and primary analyses will be performed at the hospital level. A total of ten adult surgical departments with at least 3 surgical subspecialties each will participate in the study. Sites of the study are located in 9 countries (UK, France, Spain, Germany, Switzerland, Italy, Serbia, Greece and Israel).
The primary objective is to determine the effect of an early MRSA detection \& decolonization \& isolation strategy compared to an enhanced standard control strategy on healthcare-associated MRSA isolation rates among surgical patients at risk of MRSA carriage, who are hospitalized for at least 24 hours.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 126750
- Surgical patients with LOS>24h
- Surgical patients with LOS<24h
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 1 Rapid molecular MRSA test Rapid detection 2 Hand hygiene promotion Enhanced infection control
- Primary Outcome Measures
Name Time Method Nosocomial MRSA isolation rate (expressed as the monthly rate of MRSA in clinical isolates divided by the number of susceptible patients per hundred) Monthly
- Secondary Outcome Measures
Name Time Method Nosocomial MRSA infection rate (= number of nosocomial MRSA infections per 100 admissions) Monthly
Trial Locations
- Locations (1)
Geneva University Hospitals
🇨🇭Geneva, Switzerland