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Effectiveness of High-Flow Oxygen Therapy on clinical and spirometry findings in Acute Exacerbation of Asthma

Phase 2
Conditions
Acute asthma.
Acute severe Asthma
Registration Number
IRCT2016081727929N2
Lead Sponsor
Vice-Chancellor in Research Affairs shahid Beheshti university of medical sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Admission criteria: a history of asthma; aged between 18 and 65 years; no history of smoking; no pregnancy; no history of occupational asthma

Exclusion criteria: critically ill patients requiring intensive care unit (life-threatening asthma); infiltrates on chest x-ray ; Hypercapnic respiratory failure

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Respiratory rate. Timepoint: before, 2 and 24 hours after intervention. Method of measurement: Examination.;Dyspnea score. Timepoint: before, 2 and 24 hours after intervention. Method of measurement: Borg scale.;Arterial oxygen saturation. Timepoint: before, 2 and 24 hours after intervention. Method of measurement: Arterial blood gas analysis.
Secondary Outcome Measures
NameTimeMethod
Peak expiratory flow. Timepoint: before, 2 and 24 hours after intervention. Method of measurement: peak flowmeter.;Forced expiratory volume in 1st second. Timepoint: before, 2 and 24 hours after intervention. Method of measurement: spirometry.
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