Evaluation the effect of silimaryn in improvement of hepatic and platlet damage in severe preeclampsia
- Conditions
- preeclampsia.Gestational [pregnancy-induced] hypertension with significant proteinuria
- Registration Number
- IRCT2015090423887N1
- Lead Sponsor
- Shahrekord University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 60
age between 20 and 30 years; BMI is to be 20 to 24;Gestational age is between 35 and 42 weeks at the time of termination of pregnancy; blood pressure before the termination of pregnancy is to be more than 90/140 mm Hg;The presence of Proteinuria in random urine samples before pregnancy termination; no history of hypertension, diabetes, kidney disease, Collagen vascular and other types of cardiovascular diseases; mother is supposed to be nulliparous; Singleton pregnancy not molar; termination of pregnancy is indicated By severe pre-eclampsia
Exclusion criteria:presence of preeclampsia in mother
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Platlet count. Timepoint: 0,12,36 and 60 hours after intervention. Method of measurement: count in mm3.;Blood pressure. Timepoint: q 3 hours in study. Method of measurement: mmHg.;Liver enzyme. Timepoint: before and 12,36 and 60 hours after trial. Method of measurement: labratoary kit.
- Secondary Outcome Measures
Name Time Method umber of blood pressure crisis in study. Timepoint: q 3 hours. Method of measurement: bp >160/110 mmhg.