MRI of the breast for optimal selection of patients with a preoperative diagnosis of ductal carcinoma in situ for a sentinel node biopsy procedure
Recruiting
- Conditions
- breast preneoplasiaductal carcinoma in situ10006291
- Registration Number
- NL-OMON36570
- Lead Sponsor
- Albert Schweitzer Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 150
Inclusion Criteria
Women > 25 years of age with biopsy proven DCIS are eligible for this study.
Exclusion Criteria
• claustrophobia, obesity (too big to fit into gantry of the MR system), large breast cup size (too big to fit into the coil)
• pacemaker
• known inflammatory diseases (RA, SLE, sarcoidosis, psoriasis) since these can cause reactive axillary lymfadenopathy
• pregnancy
• biopsy proven invasive carcinoma in the same breast; invasive carcinoma in the contra lateral breast is not an exclusion criterion.
• poor health excluding an operative procedure
- renal failure
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Predictive value of MRI and selected tissue markers on the presence of IDC</p><br>
- Secondary Outcome Measures
Name Time Method <p>Accuracy of MRI in determining the extent of DCIS compared to mammography. The<br /><br>size as determined by pathological examination will be the gold standard</p><br>