Clinical assessment of women with Persistent Genital Arousal Syndrome (PGAS) by quantitative sensory testing (QST) and cornea confocal microscopy (CCM)

MC0 个研究点目标入组 60 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

暂无简介。

•In order to be eligible to participate in this study, a subject must meet all of the following criteria:
•- Adult, >18 years of age
•- Able to give written informed consent
•In addition, for PGAS patients:
•- Diagnosed with PGAS, defined by the following criteria:
•i. Involuntary genital and clitoral arousal that persists for an extended period of time (hours, days, months);
•ii. The physical genital arousal does not go away following one or more orgasms;
•iii. The genital arousal is unrelated to subjective feelings of sexual desire;
•iv. The persistent feelings of genital arousal feel intrusive and unwanted; and
•v. Feelings of distress.
•In addition, for healthy controls:
•- Not diagnosed with a pain syndrome
•- Reporting an average daily pain score of NRS <2 (numerical rating scale score, range 0-10)
•- No overactive bladder symptoms or other complaints of micturition

•A potential subject who meets any of the following criteria will be excluded from participation in this study:
•PGAS patients and healthy controls:
•- Regular use of opioids (>3 of 7 days per week)
•- Diagnosis of a central nervous system disease
•- Inability to undergo quantitative sensory testing in the genital region (for whatever reason, as judged by the subject or investigator)

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