The Cognitive And Cerebral Hemodynamic Effects Of DHA-Rich Fish Oil: A Dose-Ranging Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 65
- 试验地点
- 2
- 主要终点
- Cerebral blood flow
研究概览
简要总结
DHA has previously been shown to increase regional cerebral blood flow response to tactile stimulation in aged monkeys; modulation of cerebral blood flow in humans has yet to be demonstrated. Given that the brain relies on a constant supply of blood-borne metabolic substrates (e.g. glucose, oxygen), increasing regional cerebral blood flow may also have an impact on cognitive function. The current study aims to investigate the effects of two doses of DHA-rich fish oil on task-related cerebral hemodynamic response and cognitive performance in healthy adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male/Female
- •18-35 years
- •No herbal supplements/prescription medications (excl. contraceptive pill)
- •Non smoker
- •Native English speaker
排除标准
- •consumes oily fish
- •takes omega-3 supplement
- •food allergies to treatment ingredients
结局指标
主要结局
Cerebral blood flow
时间窗: 12 weeks
Cerebral blood flow will be assessed using Near Infrared Spectroscopy while participants complete a series of cognitive tasks.
次要结局
- Cognitive function(12 weeks)
