Effects of Docosahexaenoic Acid (DHA)-Rich Fish Oil on Cerebral Haemodynamics

Not Applicable

Completed

• Conditions: Cognitive Function; Cerebral Blood Flow

• Registration Number: NCT01075932
• Lead Sponsor: Northumbria University

Brief Summary

DHA has previously been shown to increase regional cerebral blood flow response to tactile stimulation in aged monkeys; modulation of cerebral blood flow in humans has yet to be demonstrated. Given that the brain relies on a constant supply of blood-borne metabolic substrates (e.g. glucose, oxygen), increasing regional cerebral blood flow may also have an impact on cognitive function. The current study aims to investigate the effects of two doses of DHA-rich fish oil on task-related cerebral hemodynamic response and cognitive performance in healthy adults.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-04
• Primary Completion: 2009-05
• Study Completion: 2009-08
• Status Verified: 2010-02
• Study First Submitted: 2010-02-24
• Study First Submitted QC: 2010-02-24
• Last Update Submitted: 2010-02-24
• Study First Posted: 2010-02-25
• Last Update Posted: 2010-02-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 65

Inclusion Criteria

• Male/Female
• 18-35 years
• Healthy
• No herbal supplements/prescription medications (excl. contraceptive pill)
• Non smoker
• Native English speaker

Exclusion Criteria

• consumes oily fish
• takes omega-3 supplement
• food allergies to treatment ingredients

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Cerebral blood flow	12 weeks	Cerebral blood flow will be assessed using Near Infrared Spectroscopy while participants complete a series of cognitive tasks.

Secondary Outcome Measures

Name	Time	Method
Cognitive function	12 weeks	Cognitive function will be assessed using a series of tasks that evaluate working memory, attention and executive function.

Trial Locations

Locations (1)

Northumbria University; 🇬🇧 Newcastle upon Tyne, Tyne and Wear, United Kingdom