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Clinical Trials/NCT01075932
NCT01075932CompletedNot Applicable

The Cognitive And Cerebral Hemodynamic Effects Of DHA-Rich Fish Oil: A Dose-Ranging Study

Northumbria University2 sites in 1 country65 target enrollmentStarted: April 2009Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
65
Locations
2
Primary Endpoint
Cerebral blood flow
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

DHA has previously been shown to increase regional cerebral blood flow response to tactile stimulation in aged monkeys; modulation of cerebral blood flow in humans has yet to be demonstrated. Given that the brain relies on a constant supply of blood-borne metabolic substrates (e.g. glucose, oxygen), increasing regional cerebral blood flow may also have an impact on cognitive function. The current study aims to investigate the effects of two doses of DHA-rich fish oil on task-related cerebral hemodynamic response and cognitive performance in healthy adults.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Basic Science
Masking
Triple (Participant, Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to 35 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Male/Female
  • •18-35 years
  • •No herbal supplements/prescription medications (excl. contraceptive pill)
  • •Non smoker
  • •Native English speaker

Exclusion Criteria

  • •consumes oily fish
  • •takes omega-3 supplement
  • •food allergies to treatment ingredients

Outcomes

Primary Outcomes

Cerebral blood flow

Time Frame: 12 weeks

Cerebral blood flow will be assessed using Near Infrared Spectroscopy while participants complete a series of cognitive tasks.

Secondary Outcomes

  • Cognitive function(12 weeks)

Investigators

Sponsor Class
Other

Study Sites (2)

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