Evaluation of biomarkers in VTE study: the EVA study.

• Conditions: 10014523; venous thrombosis pulmonary embolism

• Registration Number: NL-OMON46107
• Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients are eligible for the study if:
- The general practitioner (GP) has a suspicion of deep venous thrombosis (DVT) or pulmonary embolism (PE), i.e. unexplained pain, swelling, and/or redness of the leg in case of DVT, or unexplained shortness of breath and pain when breathing in case of PE.
- Patients have a low score on a clinical decision rule (low pre-test probability of DVT or PE), and thus the GP aims to rule-out VTE (if possible) using routine care D-dimer testing.

Exclusion Criteria

Exclusion criteria are:
- Age below 18.
- Already using anticoagulant treatment with vitamin K antagonists, Non vitamin K Oral Anti Coagulants (NOAC) and/or low molecular-weight heparin (LMWH).
- With a non-low score on a clinical decision rule
- With an already determined POC D-dimer by the GP, suitable for risk stratification
- Life expectancy less than 3 months.
- Unwilling to participate with this study (opt-out procedure).

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified