The Outcomes of Arteriovenous Fistula (AVF) Cannulated From Different Direction in Maintenance Hemodialysis Patients.
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Prevalence of AVF aneurysm and stenosis.
研究概览
简要总结
The investigators hypothesis that aneurysms and stenoses will be decreased if the direction of inserted arterial needle were same as the direction of blood flow, when compared to the opposite direction puncture.
详细描述
Native arteriovenous fistula (AVF) is the preferred access for hemodialysis, and cannulation technique is very important factors affect the outcomes of AVF. Rope-ladder cannulation is one kind of the standard puncture techniques which is used commonly in maintenance hemodialysis (MHD) patients. There are many complications for rope-ladder cannulation, such as venous aneurysm and vascular stenosis, which may induce AVF dysfunction. For the venous outflow way, there always be aneurysm followed by stenoses at the sites of needle connected with the arterial line in rope-ladder cannulation patients. The investigators hypothesis that the directions of inserted arterial needles should affect the AVF outcomes. The present prospective study will compare the outcomes of AVF between the puncture direction at arterial needle sites same as blood flow and opposite to blood flow.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •MHD patients with autogenous AVF.
- •Newly setup AVF in 3 months.
- •Fore- or Upper arm AVF.
- •Flow of >800ml/min detected by using the ultrasound dilution technique.
排除标准
- •AVF after neoplasty.
- •Arteriovenous grafts.
- •Anticipated live time less than one year.
- •Patients whose concurrent illnesses, disability, or geographical residence would hamper attendance at required study visit.
研究组 & 干预措施
Same direction cannulation
The inserted direction of arterial needle is same as the direction of blood flow.
干预措施: Same direction cannulation (Other)
Opposite direction cannulation
The inserted direction of arterial needle is opposite to the direction of blood flow.
干预措施: Opposite direction cannulation (Other)
结局指标
主要结局
Prevalence of AVF aneurysm and stenosis.
时间窗: 12 months
Compare the prevalence of AVF aneurysm and stenosis between two groups during 12 months.
次要结局
- Events of AVF obstruction.(12 months)
- Proportions of AVF dysfunction in different groups.(12 months)
- Diameter of venous stenosis.(12 months)
- The size of venous aneurysm.(12 months)
- Percentages of unsuccessful cannulations.(12 months)
研究者
Dongliang Zhang, MD
Associated professer
Capital Medical University