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Clinical Trials/NCT01642459
NCT01642459
Terminated
Not Applicable

The Outcomes of Arteriovenous Fistula (AVF) Cannulated From Different Direction in Maintenance Hemodialysis Patients.

Dongliang Zhang, MD1 site in 1 country10 target enrollmentSeptember 2012

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Arteriovenous Fistula
Sponsor
Dongliang Zhang, MD
Enrollment
10
Locations
1
Primary Endpoint
Prevalence of AVF aneurysm and stenosis.
Status
Terminated
Last Updated
10 years ago

Overview

Brief Summary

The investigators hypothesis that aneurysms and stenoses will be decreased if the direction of inserted arterial needle were same as the direction of blood flow, when compared to the opposite direction puncture.

Detailed Description

Native arteriovenous fistula (AVF) is the preferred access for hemodialysis, and cannulation technique is very important factors affect the outcomes of AVF. Rope-ladder cannulation is one kind of the standard puncture techniques which is used commonly in maintenance hemodialysis (MHD) patients. There are many complications for rope-ladder cannulation, such as venous aneurysm and vascular stenosis, which may induce AVF dysfunction. For the venous outflow way, there always be aneurysm followed by stenoses at the sites of needle connected with the arterial line in rope-ladder cannulation patients. The investigators hypothesis that the directions of inserted arterial needles should affect the AVF outcomes. The present prospective study will compare the outcomes of AVF between the puncture direction at arterial needle sites same as blood flow and opposite to blood flow.

Registry
clinicaltrials.gov
Start Date
September 2012
End Date
April 2013
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Dongliang Zhang, MD
Responsible Party
Sponsor Investigator
Principal Investigator

Dongliang Zhang, MD

Associated professer

Capital Medical University

Eligibility Criteria

Inclusion Criteria

  • MHD patients with autogenous AVF.
  • Newly setup AVF in 3 months.
  • Fore- or Upper arm AVF.
  • Flow of \>800ml/min detected by using the ultrasound dilution technique.

Exclusion Criteria

  • AVF after neoplasty.
  • Arteriovenous grafts.
  • Anticipated live time less than one year.
  • Patients whose concurrent illnesses, disability, or geographical residence would hamper attendance at required study visit.

Outcomes

Primary Outcomes

Prevalence of AVF aneurysm and stenosis.

Time Frame: 12 months

Compare the prevalence of AVF aneurysm and stenosis between two groups during 12 months.

Secondary Outcomes

  • Events of AVF obstruction.(12 months)
  • Proportions of AVF dysfunction in different groups.(12 months)
  • Diameter of venous stenosis.(12 months)
  • The size of venous aneurysm.(12 months)
  • Percentages of unsuccessful cannulations.(12 months)

Study Sites (1)

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