Debulking Effect of Curretage on Basal Cell Carcinomas - a Histological Assessment.
Not Applicable
Completed
- Conditions
- Carcinoma, Basal Cell
- Registration Number
- NCT00237107
- Lead Sponsor
- Norwegian University of Science and Technology
- Brief Summary
The aim of this study was to compare histologically observed tumour infitration of basal cell carcinoma (bcc) lesions before and after curretage.A significant reduction of tumour depth would enable further bcc's included for superficial non-invasive treatment modalities such as topical photodynamic therapy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 36
Inclusion Criteria
- bcc with tumour depth two mm.or more
Exclusion Criteria
- bcc tumours smaller than three mm in mean diameter.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Reduction of tumour thickness 0,5mm or more after curretage 1 hour
- Secondary Outcome Measures
Name Time Method Comparison of tumour thickness in punch biopsies performed on referral, before and after curretage. 3 months
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie the debulking effect of curretage on basal cell carcinoma infiltration depth?
How does curretage compare to standard-of-care treatments for superficial basal cell carcinoma in terms of histological outcomes?
Are there specific biomarkers that correlate with tumour thickness reduction in basal cell carcinomas post-curretage?
What are the potential adverse events associated with curretage in basal cell carcinoma management and how are they managed?
What combination therapies or alternative approaches have been explored alongside curretage for basal cell carcinoma treatment?