Investigation of the Effect of Clinical Pilates Training on Functional Exercise Capacity and Respiratory Muscle Performance in Patients With Rheumatoid Arthritis
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Functional exercise capacity
研究概览
简要总结
Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with significant functional impairment and increased risk for cardiovascular and pulmonary disease. Along with pharmacological therapy, exercise seems to be a very promising intervention to improve disease-related outcomes, including functional capacity and systemic manifestations. Despite the fact that aerobic and strengthening exercises have been shown to be useful in patients with RA, there have been limited research on the effects of pilates training. Therefore, we aimed to investigate the effect of clinical pilates training on exercise capacity, respiratory and peripheral muscle strength, respiratory muscle endurance, respiratory function, pain, balance, core stability, dyspnea, functional status, fatigue, quality of life, depression and anxiety in patients with RA.
详细描述
According to sample size calculation 30 patients with RA will be included. Patients will be evaluated before and after treatment. Patients will be randomized into exercise and control training groups. In the exercise training group the patients will be given pilates exercise; in the control training group, the patients will be given relaxation exercise. Pilates exercises will be applied by the physiotherapist 3 days a week for 8 weeks. The patients in the control training group will be given relaxation exercises as a home exercise program 3 days a week for 8 weeks. Exercise capacity, pulmonary functions, respiratory and peripheral muscle strength, respiratory muscle endurance, pain, balance, core stability, dyspnea, functional status, fatigue, quality of life, depression and anxiety will be evaluated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-65 years old
- •Being diagnosed according to the American College of Rheumatology (ACR)/EULAR 2010 rheumatoid arthritis diagnostic criteria
- •under standard medications
排除标准
- •orthopedic or neurological disease with a potential to affect functional capacity
- •have problems that can prevent evaluation
- •have a neurological problem that may cause hearing or vision impairment
- •changes in medical treatment in the last 3 months
- •have high disease activity score (DAS-28>3.2)
结局指标
主要结局
Functional exercise capacity
时间窗: First day
It will be evaluated with 6-minute walking test according to the American Thoracic Society and European Respiratory Society criteria.
Pulmonary functions contains dynamic lung volumes
时间窗: First day
Spirometry will be used to perform pulmonary function testing in accordance with the American Thoracic Society and European Respiratory Society guidelines.
Respiratory muscle strength
时间窗: First day
Maximal inspiratory and expiratory muscle strength will be evaluated using mouth pressure device.
Respiratory muscle endurance
时间窗: First day
It will be assessed using an incremental threshold loading test, in which patients began with a load of 30% of maximum inspiratory pressure and increased by 10% every 2 minutes.
次要结局
- Pain level(First day)
- Core stability(Second day)
- Balance(Second day)
- Disease Specific Quality of Life(Second day)
- Functional status(First day)
- Anxiety and depression(Second day)
- Peripheral muscle strength(Second day)
- Dyspnea(First day)
- Fatigue(Second day)
研究者
Selin Bayram
Principal Investigator
Gazi University