Developmental differences in circadian rhythm establishment in preterm and term infants

Not Applicable

Completed

• Conditions: Circadian rhythm development in preterm and term infants; Reproductive Health and Childbirth - Complications of newborn; Metabolic and Endocrine - Normal metabolism and endocrine development and function

• Registration Number: ACTRN12617000346370
• Lead Sponsor: niversity of Western Australia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-03-06
• Study Completion: 2019-06-30
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 47

Inclusion Criteria

1. <28 weeks postmenstrual age
2. 28-<32 weeks postmenstrual age
3. 32-<36 weeks postmenstrual age
4. 39-41 weeks postmenstrual age

Exclusion Criteria

Any abnormality of the central nervous system
Any congenital abnormality requiring surgery in the first 4 months
Any jaundice with SBR>400 mmol/L or requiring exchange transfusion
Any hypoxic ischaemic encephalopathy (any grade)
Intraventricular haemorrhage > Gr 2
10 minute apgar score of less than 5.
Term infants with illness necessitating overnight admission to NICU
Infants with mothers that took CNS active medication whilst pregnant
Infants with mothers that partook in any substance abuse whilst pregnant
Infants with mothers that have hypothyroidism or hyperthyroidism or any other condition that affects the HPA axis.

Study & Design

• Study Type: Observational
• Study Design: Not specified