ACTRN12616001690448
Recruiting
未知
Multi-parametric Magnetic Resonance Imaging (MRI) for Therapeutic Response Prediction in Rectal Cancer
Dr Trang Pham0 sites35 target enrollmentDecember 8, 2016
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Rectal Cancer
- Sponsor
- Dr Trang Pham
- Enrollment
- 35
- Status
- Recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Age greater than 18
- •2\.Stage II or III rectal adenocarcinoma, defined as T3 \- T4 and/or node positive disease (N1\-2\), without distant metastatic disease (M0\)
- •3\.No evidence of metastatic disease on CT chest/abdomen/pelvis
- •4\.Undergoing treatment algorithm consisting of neoadjuvant chemoradiotherapy (radiotherapy 50\.4Gy in 28 fractions concurrent with infusional 5\-fluorouracil or oral capecitabine) followed by surgery at 6 to 12 weeks post chemoradiotherapy.
Exclusion Criteria
- •1\.Other malignancy
- •2\.Active inflammatory bowel disease
- •3\.On concurrent high\-dose corticosteroids (the equivalent of 50mg prednisone daily)
- •4\.Inability to have MRI due to:
- •a. Implanted magnetic metal eg. Intraocular metal
- •b. Pacemaker / Implantable defibrillator
- •c. Extreme claustrophobia.
Outcomes
Primary Outcomes
Not specified
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