DRKS00027867
Recruiting
未知
SleepLess - Imaging synaptic plasticity in therapeutic sleep deprivation for major depression - SleepLess
Forschungszentrum Jülich GmbH, Institut für Neurowissenschaften und Medizin (INM-2)0 sites60 target enrollmentJanuary 19, 2022
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- acute sleep deprivationhealthy subjects
- Sponsor
- Forschungszentrum Jülich GmbH, Institut für Neurowissenschaften und Medizin (INM-2)
- Enrollment
- 60
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age between 20 and 50
- •\- Male or female
- •\- Presentation of a written declaration of consent
- •\- For women of childbearing age: a negative pregnancy test, and use of effective contraception for at least 3 months.
- •\- Depressive disorder (ICD\-10: F32\.2 and F33\.2\)
- •\- Score of \=15 on the 21\-item Hamilton Rating Scale for Depression (HAMD).
Exclusion Criteria
- •\- BMI \> 35
- •\- Lack of a legally valid declaration of consent
- •\- Not able to speak German
- •\- Any medication with influence on the examination parameters
- •\- Blood\-thinning medication or known (diagnosed) coagulation disorders
- •\- Chronic diseases: e.g. neurological, cardiopulmonary, endocrinological, renal, hepatic, psychiatric (except depressive disorder), autoimmunological diseases
- •\- DSM\-V Axis I disorder (lifetime) other than depressive disorder, such as schizophrenia, schizoaffective disorder, other non\-bipolar mental disorders, bipolar disorder, primary anxiety disorder or obsessive\-compulsive disorder, mental retardation, signs of impaired cognitive performance
- •\- psychotic symptoms, suicidal intentions
- •\- sleep disturbances in healthy subjects
- •\- Shift and night work
Outcomes
Primary Outcomes
Not specified
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