Association between brain atrophy and intestinal permeability in patients with multiple sclerosis
Not Applicable
- Conditions
- multiple sclerosis
- Registration Number
- JPRN-UMIN000043910
- Lead Sponsor
- Department of Neurology and Neurological Science, Tokyo Medical and Dental University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
Persons who have 1. pace makers or magnetic metals 2. claustrophobia 3. unstable general condition and vital signs 4. difficulty in informed consent 5. cancers or inflammatory bowel disease 6. diabetes mellitus , pregnant women and persons who is not suitable for the participants according to the doctor's decision.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation between the rate of brain atrophy over 48 months and intestinal permeability measured at baseline.
- Secondary Outcome Measures
Name Time Method Association between intestinal permeability at baseline and disease subtypes, disability, cognition, brain volume and disease modifying therapy