Abnormal number of fetal ribs or vertebrae and associated congenital abnormalities and adverse fetal outcome; The need for prenatal detection of rib and vertebral abnormalities by 2D&3D-ultrasound.

Completed

• Conditions: rib and vertebral anomalies; vertebral column abnormalities; 10027664; 10016849

• Registration Number: NL-OMON40300
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 260

Inclusion Criteria

Pregnant women
- with a gestational age of at least 12 weeks
- of at least 18 years old
- who are mentally competent
- who are willing to sign the informed consent form

Exclusion Criteria

Language barrier
No consensus on interpretation of ultrasound or Xrays between different observers
Insufficient ossification (taking visibility of ossification centres of the phalanges as a reference)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The number of ribs and/or vertebrae in fetuses with and without congenital<br /><br>malformations, aneuploidy and adverse fetal outcome.</p><br>