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临床试验/EUCTR2008-005055-23-IT
EUCTR2008-005055-23-IT进行中(未招募)不适用

TREATMENT OF HYPERPARATHYROIDISM IN PATIENTS WITH MULTIPLE ENDOCRINE NEOPLASIA TYPE 1 (MEN1) WITH THE CALCIMIMETIC AGENT CINACALCET - ND

OSPEDALE MAGGIORE DI MILANO (IRCCS)0 个研究点开始时间: 2010年3月11日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • ? Age > 18 years ? Total serum calcium > 10.4 mg/dl and < 13 mg/dl (at least 2 consecutive evaluations within the last 6 months) ? Ionized serum calcium > 1.32 mmol/L ? PTH > 65 pg/ml (at least 2 consecutive evaluations within the last 6 months) ? 25(OH)-vitamin D > 30 ng/ml
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) no
  • F.1.3.1 Number of subjects for this age range

排除标准

  • ? Pregnancy ? Chronic kidney disease ? Chronic hepatic ? Treatment with drugs metabolized by hepatic cytochrome P450 2D6 (CPY2D6), inhibitors or inducers of CYP3A4 and/or CYP1A2 ? Treatment with biphosphonates or fluoride within (60 days before baseline) ? Treatment with anti convulsive drugs or positive history of epilepsy or convulsions. ? Secondary hyperparathyroidism ? Other causes of hypercalcemia

研究者

发起方
OSPEDALE MAGGIORE DI MILANO (IRCCS)

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