EUCTR2008-005055-23-IT进行中(未招募)不适用
TREATMENT OF HYPERPARATHYROIDISM IN PATIENTS WITH MULTIPLE ENDOCRINE NEOPLASIA TYPE 1 (MEN1) WITH THE CALCIMIMETIC AGENT CINACALCET - ND
OSPEDALE MAGGIORE DI MILANO (IRCCS)0 个研究点开始时间: 2010年3月11日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中(未招募)
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •? Age > 18 years ? Total serum calcium > 10.4 mg/dl and < 13 mg/dl (at least 2 consecutive evaluations within the last 6 months) ? Ionized serum calcium > 1.32 mmol/L ? PTH > 65 pg/ml (at least 2 consecutive evaluations within the last 6 months) ? 25(OH)-vitamin D > 30 ng/ml
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •? Pregnancy ? Chronic kidney disease ? Chronic hepatic ? Treatment with drugs metabolized by hepatic cytochrome P450 2D6 (CPY2D6), inhibitors or inducers of CYP3A4 and/or CYP1A2 ? Treatment with biphosphonates or fluoride within (60 days before baseline) ? Treatment with anti convulsive drugs or positive history of epilepsy or convulsions. ? Secondary hyperparathyroidism ? Other causes of hypercalcemia
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