Quantitative analysis of heart rate variability (HRV) in children and adolescents with epilepsy

• Conditions: G40; Epilepsy

• Registration Number: DRKS00030750
• Lead Sponsor: niversitätsklinikum Freiburg, Zentrum für Kinder- und Jugendmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-04
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 293

Inclusion Criteria

Children and adolescents between the ages of 0 and 14 years with a diagnosis of epilepsy, who received video-EEG-monitoring from 1999 to 2018 at the Freiburg Epilepsy Center for clinical reasons. At least one seizure must have occurred during the monitoring. Furthermore, at least a 10-minute interictal period prior to the analyzed seizure must have been recorded in the examined patients in order to obtain a meaningful measurement of the basal heart rate.

Exclusion Criteria

Exclusion criteria include age over 14 years, the occurrence of no or only subclinical seizures and a diagnosed independent cardiac disease.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Detailed description and analysis of HRV in children and adolescents with epilepsy.

Secondary Outcome Measures

Name	Time	Method
Identification of a subgroup of patients who are statistically more likely to have lower HRV and may therefore be at increased risk of SUDEP.