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临床试验/NCT05090423
NCT05090423
已完成
不适用

The Effect of Additional Neurodynamic Intervention in Patients With Chronic Ankle Instability

National Yang Ming Chiao Tung University1 个研究点 分布在 1 个国家目标入组 36 人2022年1月5日
适应症Ankle Sprains

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Ankle Sprains
发起方
National Yang Ming Chiao Tung University
入组人数
36
试验地点
1
主要终点
Pressure Pain Threshold- Anterior Talofibular Ligament
状态
已完成
最后更新
3个月前

概览

简要总结

Approximately 40% of acute ankle sprain would develop into chronic ankle instability (CAI). Chronic ankle instability is characterized by pain, repeated sprains and giving way. Recently, the pathomechanical impairment, sensory-perceptual impairment and motor-behavioral impairment have been documented in the chronic ankle instability model. Previous research revealed that compared to the control subjects, people with CAI had lower pressure pain threshold (PPT). This increased mechanosensitivity of the neural tissues around the ankle might account for pain and dysfunction in people with CAI. Also, the other study indicated that in subjects following ankle inversion sprain there is greater restriction of knee extension on the injured side compared to non-injured side in the slump test with the ankle plantar flexion and inversion, which may suggest the restriction in mobility of the common peroneal tract. However, the effects of neurodynamic intervention, which addresses the mechanosensitivity problems, in people with CAI are still unclear.

Therefore, the aim of the study is to investigate the effect of additional neurodynamic intervention on the ankle range of motion, mechanosensitivity, balance performance and self-reported function.

详细描述

Chronic ankle instability (CAI) is characterized by pain, repeated sprains and giving way. Approximately 40% of acute ankle sprain would develop into chronic ankle instability. Recently, the pathomechanical impairment, sensory-perceptual impairment and motor-behavioral impairment have been documented in the chronic ankle instability model. Previous research revealed that compared to the control subjects, people with CAI had lower pressure pain threshold (PPT). This increased mechanosensitivity of the neural tissues around the ankle might account for pain and dysfunction in people with CAI. Pahor et al., indicated that in subjects following ankle inversion sprain there is greater restriction of knee extension on the injured side compared to non-injured side in the slump test with the ankle plantar flexion and inversion, which may suggest the restriction in mobility of the common peroneal tract. However, the effects of neurodynamic intervention, which addresses the mechanosensitivity problems, in people with CAI are still unclear. Purpose: The aim of the study is to investigate the effects of neurodynamic intervention on the mechanosensitivity, balance performance and self-reported function in patients with CAI. Study design: A randomized controlled trial design. Single-blinded. Methods: Forty subjects between 20-50 with CAI were recruited and randomized into either the exercise only group or the neurodynamic intervention with exercise (neurodynamic) group. The sample size was calculated based on the PPT data of Lorenzo-Sanchez-Aguilera et al's, which requires 20 subjects in each group to reach a statistical power of 0.8. Both groups were receive 12 interventions within 6-8 weeks. The exercise only group performed balance training, while the neurodynamic group received balance training and neurodynamic intervention for the common peroneal nerve. Outcome measures included demographic data, pressure pain threshold, active knee extension range of motion (ROM) of the slump test with ankle plantarflexion and inversion (AKEOST), hamstrings flexibility, ankle range of motion, Y balance test and foot and ankle ability measure (FAAM).

注册库
clinicaltrials.gov
开始日期
2022年1月5日
结束日期
2024年6月30日
最后更新
3个月前
研究类型
Interventional
研究设计
Parallel
性别
All

研究者

责任方
Principal Investigator
主要研究者

Yi-Fen Shih

Professor

National Yang Ming Chiao Tung University

入排标准

入选标准

  • History of at least two ankle sprains in the same leg, of which the first sprain is more than one year
  • Leading to at least one interrupted day of desired physical activity
  • The Cumberland Ankle Instability Tool (CAIT) ≦ 24
  • Slump test in ankle plantar flexion with inversion: positive

排除标准

  • Surgical treatments
  • Previous fractures in either lower extremity
  • Any concomitant lower extremity pathology, for example, vascular disease, osteoarthritis and rheumatoid arthritis
  • Significant pain or injury to the lumbar or cervical spine
  • Regular use of medication: anti-inflammatory drugs, painkiller, steroid or muscle relaxants
  • Previous manual therapy or exercise interventions received on the lower extremity within the previous 3 months

结局指标

主要结局

Pressure Pain Threshold- Anterior Talofibular Ligament

时间窗: Within one week after 12 treatment sessions

Using the PainTestTM FDX algometer, apply vertical contact and average force to measure pressure pain thresholds at the anterior talofibular ligament. The point is tested three times with a 30-second interval between tests, and the average of the three measurements is recorded.

Pressure Pain Threshold- Calcaneofibular Ligament

时间窗: Within one week after 12 treatment sessions

Using the PainTestTM FDX algometer, apply vertical contact and average force to measure pressure pain thresholds at the calcaneofibular ligament. The point is tested three times with a 30-second interval between tests, and the average of the three measurements is recorded.

Active Knee Extension Range of Motion During Slump Test in Ankle Plantar Flexion With Inversion

时间窗: Within one week after 12 treatment session

The subjects sat on the edge of the bed without touching the ground with their feet. The physical therapist assisted the subjects in maintaining a neutral pelvis position. First, the subjects were asked to flex the neck, trunk, and finally the lumbar to tighten the back. Second, while the subjects plantarflexed and inverted the ankle, they performed the knee extension movement, and the angle of knee motion was recorded. Participants performed three practice trials followed by three test trials and averaged the three tests.

Pressure Pain Threshold- Peroneal Brevis Muscle

时间窗: Within one week after 12 treatment sessions

Using the PainTestTM FDX algometer, apply vertical contact and average force to measure pressure pain thresholds at the peroneal brevis muscle. The point is tested three times with a 30-second interval between tests, and the average of the three measurements is recorded.

Pressure Pain Threshold- Peroneal Longus Muscle

时间窗: Within one week after 12 treatment sessions

Using the PainTestTM FDX algometer, apply vertical contact and average force to measure pressure pain thresholds at the peroneal longus muscle. The point is tested three times with a 30-second interval between tests, and the average of the three measurements is recorded.

Pressure Pain Threshold- Common Peroneal Nerve

时间窗: Within one week after 12 treatment sessions

Using the PainTestTM FDX algometer, apply vertical contact and average force to measure pressure pain thresholds at the common peroneal nerve. The point is tested three times with a 30-second interval between tests, and the average of the three measurements is recorded.

次要结局

  • Y Balance Test- Anterior Direction(Within one week after 12 treatment sessions)
  • The Foot and Ankle Ability Measures- Sports(Within one week after 12 treatment sessions)
  • The Foot and Ankle Ability Measures- Activity of Life(Within one week after 12 treatment sessions)
  • Weight Bearing Lunge Test(Within one week after 12 treatment sessions)
  • Hamstring Flexibility(Within one week after 12 treatment sessions)
  • The Foot and Ankle Ability Measures- Activity of Life (Self- Awareness Score)(Within one week after 12 treatment sessions)
  • The Foot and Ankle Ability Measures- Sports (Self- Awareness Score)(Within one week after 12 treatment sessions)
  • Y Balance- Posterolateral Direction(Within one week after 12 treatment sessions)
  • Y Balance- Posteromedial Direction(Within one week after 12 treatment sessions)

研究点 (1)

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